| Catalog number: | bs-0518R-A647 |
|---|---|
| Price: | 350 € |
| Supplier: | Bioss Primary Conjugated Antibodies. |
| Product name: | ATF2 Antibody, ALEXA FLUOR 647 |
| Quantity: | 100ul |
| Related search: |
| Long name: | ALEXA FLUOR 647 Conjugated, ATF2 Polyclonal Antibody |
|---|---|
| Also known as: | Anti-ATF2 PAb ALEXA FLUOR 647 |
| Category: | Conjugated Primary Antibodies |
| Conjugated with: | 647, ALEXA FLUOR® |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | ATF2 |
| Specificity: | This is a highly specific antibody against ATF2 |
| Modification: | Unmodified |
| Modification Site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Immunogen range: | 415-455/505 |
| Subcellular location: | Mitochondrion, Nucleus, Cytoplasm |
| Source: | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ATF2 |
| Gene ID Number: | 1386 |
| Swiss Prot: | P15336 |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Mouse, Rat, Human |
| Cross-reactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: | Can elicit oncogenic or tumor suppressor activities depending on the tissue or cell type, Dependent on its binding partner, Exhibits histone acetyltransferase (HAT) activity which specifically acetylates histones H2B and H4 in vitro, In concert with CUL3 and RBX1, In the cytoplasm, In the nucleus, The phosphorylated form (mediated by ATM) plays a role in the DNA damage response and is involved in the ionizing radiation (IR)-induced S phase checkpoint control and in the recruitment of the MRN complex into the IR-induced foci (IRIF), and DNA damage response, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA-3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA-3'), cell growth, contributes to global transcription and the DNA damage response, in addition to specific transcriptional activities that are related to cell development, including those involved in anti-apoptosis, inducing mitochondrial leakage and promoting cell death, interacts with and perturbs HK1- and VDAC1-containing complexes at the mitochondrial outer membrane, proliferation and death, promotes the degradation of KAT5 thereby attenuating its ability to acetylate and activate ATM, thereby impairing mitochondrial membrane potential, Transcriptional activator which regulates the transcription of various genes |
| Purification: | Purified by Protein A |
| Storage conditions: | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: | 650nm/665nm |
| Synonyms: | ATF1 ATF2 HFB1-GDNF |
| Properties: | ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the ATF2 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: | ALEXA FLUOR 647, Alexa Fluor |
| Gene target: | ATF2 |
| Short name: | ATF2 Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Label: | ALEXA FLUOR 647 |
| Alternative name: | ALEXA FLUOR 647, ATF2 (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 4232 |
| Gene: | GDNF | More about : GDNF |
| Long gene name: | glial cell derived neurotrophic factor |
| Synonyms name: | astrocyte-derived trophic factor glial cell line derived neurotrophic factor glial derived neurotrophic factor |
| Locus: | 5p13, 2 |
| Discovery year: | 1995-05-04 |
| Entrez gene record: | 2668 |
| Pubmed identfication: | 8493557 |
| RefSeq identity: | NM_000514 |
| Classification: | Endogenous ligands |
| Havana BLAST/BLAT: | OTTHUMG00000090809 |
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| bs-5169R-A488 | ATF2 (Ser322) Antibody, ALEXA FLUOR 488 | 100ul | 350 € | Bioss Primary Conjugated Antibodies. | human |
| bs-5169R-A555 | ATF2 (Ser322) Antibody, ALEXA FLUOR 555 | 100ul | 350 € | Bioss Primary Conjugated Antibodies. | human |
| bs-5169R-A594 | ATF2 (Ser322) Antibody, ALEXA FLUOR 594 | 100ul | 350 € | Bioss Primary Conjugated Antibodies. | human |
| bs-5170R-A350 | ATF2 (Ser44) Antibody, ALEXA FLUOR 350 | 100ul | 350 € | Bioss Primary Conjugated Antibodies. | human |
| bs-5170R-A488 | ATF2 (Ser44) Antibody, ALEXA FLUOR 488 | 100ul | 350 € | Bioss Primary Conjugated Antibodies. | human |
| bs-5170R-A555 | ATF2 (Ser44) Antibody, ALEXA FLUOR 555 | 100ul | 350 € | Bioss Primary Conjugated Antibodies. | human |
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| bs-12536R-A488 | ATF2 (Ser480) Antibody, ALEXA FLUOR 488 | 100ul | 350 € | Bioss Primary Conjugated Antibodies. | human |
| bs-12536R-A555 | ATF2 (Ser480) Antibody, ALEXA FLUOR 555 | 100ul | 350 € | Bioss Primary Conjugated Antibodies. | human |
| bs-12536R-A594 | ATF2 (Ser480) Antibody, ALEXA FLUOR 594 | 100ul | 350 € | Bioss Primary Conjugated Antibodies. | human |
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| bs-12537R-A488 | ATF2 (Thr51 + Thr53) Antibody, ALEXA FLUOR 488 | 100ul | 350 € | Bioss Primary Conjugated Antibodies. | human |
| bs-12537R-A555 | ATF2 (Thr51 + Thr53) Antibody, ALEXA FLUOR 555 | 100ul | 350 € | Bioss Primary Conjugated Antibodies. | human |
| bs-12537R-A594 | ATF2 (Thr51 + Thr53) Antibody, ALEXA FLUOR 594 | 100ul | 350 € | Bioss Primary Conjugated Antibodies. | human |
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