| Catalog number: | bs-0497R-Biotin |
|---|---|
| Price: | 603 € |
| Supplier: | MBS Polyclonals |
| Product name: | Dnmt3a Antibody, Biotin Conjugated |
| Quantity: | 0.2 ml |
| Related search: |
| Long name: | Biotin Conjugated, Dnmt3a Polyclonal Antibody |
|---|---|
| Category: | Conjugated Primary Antibodies |
| Conjugation: | Biotinylated |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | Dnmt3a |
| Specificity: | This is a highly specific antibody against Dnmt3a |
| Modification: | Unmodified |
| Modification site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Subcellular location: | Nucleus, Cytoplasm |
| Source: | KLH conjugated synthetic peptide derived from human Dnmt3a |
| Gene ID number: | 1788 |
| Swiss Prot: | Q9Y6K1 |
| Tested applications: | IHC-P, WB |
| Recommended dilutions: | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: | Mouse, Rat, Human |
| Crossreactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: | Acts as a transcriptional corepressor for ZBTB18, Can actively repress transcription through the recruitment of HDAC activity, DNA methylation is coordinated with methylation of histones, It modifies DNA in a non-processive manner and also methylates non-CpG sites, May preferentially methylate DNA linker between 2 nucleosomal cores and is inhibited by histone H1, Plays a role in paternal and maternal imprinting, Recruited to trimethylated 'Lys-36' of histone H3 (H3K36me3) sites, Required for methylation of most imprinted loci in germ cells, Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development |
| Purification method: | This antibody was purified via Protein A |
| Storage conditions: | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: | DNA (cytosine-5)-methyltransferase 3A, DNA MTase HsaIIIA, DNA methyltransferase HsaIIIA, DNMT3A2, Dnmt3a, M, HsaIIIA, TBRS |
| Properties: | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: | Dnmt3a Conjugated |
| Short name: | Conjugated, Dnmt3a Antibody |
| Technique: | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: | Biotin |
| Alternative name: | biotinilated coupled, Dnmt3a (Antibody to) |
| Alternative technique: | antibodies |
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