| Long name: |
Cy3 Conjugated, PPP4C Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
cy3 conjugation kit |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
PPP4C |
| Specificity: |
This is a highly specific antibody against PPP4C |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
260-307/307 |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from human PP4C |
| Gene ID number: |
5531 |
| Swiss Prot: |
P60510 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
DNA damage checkpoint signaling, DNA repair, Dephosphorylates NDEL1 at CDK1 phosphorylation sites and negatively regulates CDK1 activity in interphase (By similarity), In response to DNA damage, NF-kappa-B activation and cell migration, The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3, The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on Ser-14 (gamma-H2AFX) generated during DNA replication and required for DNA double strand break repair, activation of c-Jun N-terminal kinase MAPK8, an essential step for DNA repair since it allows the efficient RPA2-mediated recruitment of RAD51 to chromatin, apoptosis, catalyzes RPA2 dephosphorylation, maturation of spliceosomal snRNPs, regulation of histone acetylation, tumor necrosis factor (TNF)-alpha signaling, Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
512, 550nm/570, 615nm |
| Synonyms: |
PP4 PPX |
| Properties: |
1 of the PPP4C Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
PPP4C Conjugated |
| Short name: |
Conjugated, PPP4C Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy3 |
| Alternative name: |
cyanine 3 coupled, PPP4C (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9319 |
| Gene: |
PPP4C |
More about : PPP4C |
| Long gene name: |
protein phosphatase 4 catalytic subunit |
| Synonyms gene name: |
catalytic subunit , catalytic subunit protein phosphatase 4, protein phosphatase 4 (formerly X) |
| Synonyms name: |
catalytic subunit , protein phosphatase X |
| Locus: |
16p11, 2 |
| Discovery year: |
1993-01-22 |
| Entrez gene record: |
5531 |
| Pubmed identfication: |
9177794 |
| RefSeq identity: |
NM_002720 |
| Classification: |
Protein phosphatase catalytic subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000132113 |