| Long name: |
Slc22A17 Primary Polyclonal Antibody |
| Also known as: |
Slc22A17 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Slc22A17 |
| Specificity: |
This is a highly specific antibody against Slc22A17 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
500-538/538 |
| Subcellular location: |
Cell membrane |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SLC22A17 |
| Gene ID number: |
51310 |
| Swiss Prot: |
Q8WUG5 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Able to bind iron-bound LCN2 (holo-24p3), Also binds iron-free LCN2 (apo-24p3), followed by internalization of apo-24p3 and its association with an intracellular siderophore, followed by internalization of holo-24p3 and release of iron, leading to iron chelation and iron transfer to the extracellular medium, thereby increasing intracellular iron concentration and leading to inhibition of apoptosis, thereby reducing intracellular iron concentration and resulting in apoptosis (By similarity), Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
24p3 receptor, 24p3R, BOIT, Brain-type organic cation transporter, Lipocalin-2 receptor, NGALR, NGALR2, NGALR3, Neutrophil gelatinase-associated lipocalin receptor, SLC22A17, Solute carrier family 22 member 17, hBOIT, BOCT |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Slc22A17 |
| Short name: |
Slc22A17 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Slc22A17 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
23095 |
| Gene: |
SLC22A17 |
More about : SLC22A17 |
| Long gene name: |
solute carrier family 22 member 17 |
| Synonyms gene name: |
member 17 , solute carrier family 22 |
| Synonyms: |
BOCT BOIT NGALR |
| Synonyms name: |
neutrophil gelatinase-associated lipocalin receptor |
| Locus: |
14q11, 2 |
| Discovery year: |
2003-09-24 |
| GenBank acession: |
AJ243653 |
| Entrez gene record: |
51310 |
| Pubmed identfication: |
16377569 |
| RefSeq identity: |
NM_020372 |
| Classification: |
Solute carriers |
| Havana BLAST/BLAT: |
OTTHUMG00000028740 |