| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Slc22A17 |
| Specificity: |
This antibody reacts specifically with Slc22A17 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Cell membrane |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human SLC22A17 |
| Gene ID: |
51310 |
| Swiss Prot: |
Q8WUG5 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Able to bind iron-bound LCN2 (holo-24p3), Also binds iron-free LCN2 (apo-24p3), followed by internalization of apo-24p3 and its association with an intracellular siderophore, followed by internalization of holo-24p3 and release of iron, leading to iron chelation and iron transfer to the extracellular medium, thereby increasing intracellular iron concentration and leading to inhibition of apoptosis, thereby reducing intracellular iron concentration and resulting in apoptosis (By similarity), Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
BOCT BOIT NGALR |
| Also known as: |
Slc22A17 Polyclonal Antibody |
| Other name: |
Anti-Slc22A17 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Slc22A17 |
| Short name: |
Anti-Slc22A17 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Slc22A17 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
23095 |
| Gene: |
SLC22A17 |
More about : SLC22A17 |
| Long gene name: |
solute carrier family 22 member 17 |
| Synonyms gene name: |
member 17 , solute carrier family 22 |
| Synonyms name: |
neutrophil gelatinase-associated lipocalin receptor |
| Locus: |
14q11, 2 |
| Discovery year: |
2003-09-24 |
| GenBank acession: |
AJ243653 |
| Entrez gene record: |
51310 |
| Pubmed identfication: |
16377569 |
| RefSeq identity: |
NM_020372 |
| Classification: |
Solute carriers |
| Havana BLAST/BLAT: |
OTTHUMG00000028740 |