| Long name: |
TIMP-1 Primary Polyclonal Antibody |
| Also known as: |
TIMP-1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
TIMP-1NT |
| Specificity: |
This is a highly specific antibody against TIMP-1NT |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
95-145/207 |
| Subcellular location: |
Secreted |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TIMP-1 |
| Gene ID number: |
7076 |
| Swiss Prot: |
P01033 |
| Tested Applications: |
IF(ICC), IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(ICC)(1:50-200), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Acts on MMP1, Also functions as a growth factor that regulates cell differentiation, Does not act on MMP14, MMP1, MMP11, MMP12, MMP13 and MMP16, MMP2, MMP3, MMP7, MMP8, MMP9, Mediates erythropoiesis in vitro, Plays a role in integrin signaling, and irreversibly inactivates them by binding to their catalytic zinc cofactor, but, it is species-specific, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1, stimulating the growth and differentiation of only human and murine erythroid progenitors, such as collagenases, unlike IL3, Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CLGI, Collagenase inhibitor, EPO, Erythroid-potentiating activity, Fibroblast collagenase inhibitor, HCI, Metalloproteinase inhibitor 1, TIMP, TIMP-1, TIMP1, Tissue inhibitor of metalloproteinases 1, EPA |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
TIMP-1 |
| Short name: |
TIMP-1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
TIMP-1 (Antibody to) |
| Alternative technique: |
antibodies |