| Long name: |
Biotin Conjugated, TIMP-1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
TIMP-1NT |
| Specificity: |
This is a highly specific antibody against TIMP-1NT |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
95-145/207 |
| Subcellular location: |
Secreted |
| Source: |
KLH conjugated synthetic peptide derived from human TIMP-1 |
| Gene ID number: |
7076 |
| Swiss Prot: |
P01033 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Acts on MMP1, Also functions as a growth factor that regulates cell differentiation, Does not act on MMP14, MMP1, MMP11, MMP12, MMP13 and MMP16, MMP2, MMP3, MMP7, MMP8, MMP9, Mediates erythropoiesis in vitro, Plays a role in integrin signaling, and irreversibly inactivates them by binding to their catalytic zinc cofactor, but, it is species-specific, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1, stimulating the growth and differentiation of only human and murine erythroid progenitors, such as collagenases, unlike IL3, Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
CLGI, Collagenase inhibitor, EPO, Erythroid-potentiating activity, Fibroblast collagenase inhibitor, HCI, Metalloproteinase inhibitor 1, TIMP, TIMP-1, TIMP1, Tissue inhibitor of metalloproteinases 1, EPA |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
TIMP-1 Conjugated |
| Short name: |
Conjugated, TIMP-1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, TIMP-1 (Antibody to) |
| Alternative technique: |
antibodies |