| Long name: |
ALEXA FLUOR 647 Conjugated, Fas Ligand Polyclonal Antibody |
| Also known as: |
Anti-Fas Ligand PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Fas Ligand |
| Specificity: |
This is a highly specific antibody against Fas Ligand |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
170-220/281 |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Fas Ligand |
| Gene ID Number: |
356 |
| Swiss Prot: |
P48023 |
| Tested applications: |
IF(IHC-P), FCM |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects, May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development, TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, The FasL intracellular domain (FasL ICD) cytoplasmic form induces gene transcription inhibition, a receptor that transduces the apoptotic signal into cells, in the antigen-stimulated suicide of mature T-cells, or both, Cytokine that binds to TNFRSF6/FAS |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
FasL CD178 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the Fas Ligand Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Description: |
Receptor agonists are often tested for drug development, FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling |
| Gene target: |
Fas Ligand |
| Short name: |
Fas Ligand Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, member 6) Ligand (Antibody to), Fas (TNF receptor superfamily |
| Alternative technique: |
antibodies |
| Identity: |
11936 |
| Gene: |
FASLG |
More about : FASLG |
| Long gene name: |
Fas ligand |
| Synonyms gene: |
APT1LG1 TNFSF6 |
| Synonyms gene name: |
member 6 Fas ligand (TNF superfamily, member 6) , tumor necrosis factor (ligand) superfamily |
| Locus: |
1q24, 3 |
| Discovery year: |
1994-12-09 |
| GenBank acession: |
U11821 |
| Entrez gene record: |
356 |
| Pubmed identfication: |
7826947 9022072 |
| Classification: |
Endogenous ligands Tumor necrosis factor superfamily CD molecules Death inducing signaling complex |
| Havana BLAST/BLAT: |
OTTHUMG00000034841 |
| Locus Specific Databases: |
FASLGbase: Mutation registry for Autoimmune lymphoproliferative syndrome, type 1B (ALPS1B) (previously known as TNFSF6base) LRG_58 |