| Long name: |
ALEXA FLUOR 594 Conjugated, Fas Ligand Polyclonal Antibody |
| Also known as: |
Anti-Fas Ligand PAb ALEXA FLUOR 594 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Fas Ligand |
| Specificity: |
This is a highly specific antibody against Fas Ligand |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
170-220/281 |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Fas Ligand |
| Gene ID Number: |
356 |
| Swiss Prot: |
P48023 |
| Tested applications: |
IF(IHC-P), FCM |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects, May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development, TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, The FasL intracellular domain (FasL ICD) cytoplasmic form induces gene transcription inhibition, a receptor that transduces the apoptotic signal into cells, in the antigen-stimulated suicide of mature T-cells, or both, Cytokine that binds to TNFRSF6/FAS |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
FasL CD178 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated: |
Alexa conjugate 1 |
| Description: |
Receptor agonists are often tested for drug development, FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling |
| Gene target: |
Fas Ligand |
| Short name: |
Fas Ligand Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 594 |
| Alternative name: |
ALEXA FLUOR 594, member 6) Ligand (Antibody to), Fas (TNF receptor superfamily |
| Alternative technique: |
antibodies |
| Identity: |
11936 |
| Gene: |
FASLG |
More about : FASLG |
| Long gene name: |
Fas ligand |
| Synonyms gene: |
APT1LG1 TNFSF6 |
| Synonyms gene name: |
member 6 Fas ligand (TNF superfamily, member 6) , tumor necrosis factor (ligand) superfamily |
| Locus: |
1q24, 3 |
| Discovery year: |
1994-12-09 |
| GenBank acession: |
U11821 |
| Entrez gene record: |
356 |
| Pubmed identfication: |
7826947 9022072 |
| Classification: |
Endogenous ligands Tumor necrosis factor superfamily CD molecules Death inducing signaling complex |
| Havana BLAST/BLAT: |
OTTHUMG00000034841 |
| Locus Specific Databases: |
FASLGbase: Mutation registry for Autoimmune lymphoproliferative syndrome, type 1B (ALPS1B) (previously known as TNFSF6base) LRG_58 |