| Long name: |
ALEXA FLUOR 488 Conjugated, PTP1B Polyclonal Antibody |
| Also known as: |
Anti-PTP1B PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
PTP1B |
| Specificity: |
This is a highly specific antibody against PTP1B |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
13-65/435 |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PTP-1B |
| Gene ID Number: |
5770 |
| Swiss Prot: |
P18031 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
May also regulate the hepatocyte growth factor receptor signaling pathway through dephosphorylation of MET, May play an important role in CKII- and p60c-src-induced signal transduction cascades, May regulate the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion, Mediates dephosphorylation of EIF2AK3/PERK, inactivating the protein kinase activity of EIF2AK3/PERK, Tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the PTP1B Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
PTP1B |
| Short name: |
PTP1B Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, PTP1B (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9642 |
| Gene: |
PTPN1 |
More about : PTPN1 |
| Long gene name: |
non-receptor type 1 , protein tyrosine phosphatase |
| Synonyms gene: |
PTP1B |
| Locus: |
20q13, 13 |
| Discovery year: |
1991-09-13 |
| Entrez gene record: |
5770 |
| Pubmed identfication: |
2164224 |
| Classification: |
Protein tyrosine phosphatases, non-receptor type |
| Havana BLAST/BLAT: |
OTTHUMG00000032729 |