| Long name: |
Nociceptin receptor Primary Polyclonal Antibody |
| Also known as: |
Nociceptin receptor PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Nociceptin receptor |
| Specificity: |
This is a highly specific antibody against Nociceptin receptor |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
1-40/367 |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from mouse Nociceptin receptor |
| Gene ID number: |
18389 |
| Swiss Prot: |
P35377 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Arrestins modulate signaling via G proteins and mediate the activation of alternative signaling pathways that lead to the activation of MAP kinases, Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, Plays a role in modulating nociception and the perception of pain, Plays a role in the regulation of locomotor activity by the neuropeptide nociceptin, Signaling via G proteins mediates inhibition of adenylate cyclase activity and calcium channel activity, G-protein coupled opioid receptor that functions as receptor for the endogenous neuropeptide nociceptin |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
K3 opiate receptor, KOR-3, Kappa-type 3 opioid receptor, LC132, MOR-C, Nociceptin receptor, ORGC, ORL1, Oor, Oprl, Oprl1, Orphanin FQ receptor, XOR1, morc, KOR3 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Description: |
2 or 3 and , However, In this sense, When such chemical-signals couple or bind to a receptor, a change in the electrical-activity of a cell, acetylcholine, am olfactory receptor is a protein-molecule that recognizes and responds to , an acetylcholine-receptor recognizes and responds to its endogenous-ligand, chemokinesor cytokines e, e, sometimes in pharmacology, such as enzymes, the term is also used to include other proteins that are drug-targets, they cause some form of cellular/tissue-response, transporters and ion-channels, The receptors are ligand binding factors of type 1, endogenous-chemical signals, g, g, protein-molecules , that receive chemical-signals from outside a cell |
| Gene target: |
Nociceptin receptor |
| Short name: |
Nociceptin receptor Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Nociceptin receptor (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
8155 |
| Gene: |
OPRL1 |
More about : OPRL1 |
| Long gene name: |
opioid related nociceptin receptor 1 |
| Synonyms gene name: |
opiate receptor-like 1 |
| Synonyms: |
NOCIR ORL1 OOR KOR-3 NOPr |
| Synonyms name: |
LC132 receptor-like orphanin FQ receptor kappa3-related opioid receptor nociceptin/orphanin FQ receptor |
| Locus: |
20q13, 33 |
| Discovery year: |
1996-05-28 |
| Entrez gene record: |
4987 |
| Pubmed identfication: |
8137918 17910740 |
| RefSeq identity: |
NM_182647 |
| Classification: |
Opioid receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000033027 |