TrkB Antibody, PE Conjugated

Catalog number:	bs-0175R-PE Buy Now
Price:	368 €
Supplier:	Bioss Primary Conjugated Antibodies
Product name:	TrkB Antibody, PE Conjugated
Quantity:	0.1ml
Related search:	trkb antibody antibodies kinase shb tyrosine cascade

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Long name:	PE Conjugated, TrkB Polyclonal Antibody
Category:	Conjugated Primary Antibodies
Conjugation:	PE
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	TrkB
Specificity:	This is a highly specific antibody against TrkB
Modification:	Unmodified
Modification site:	None
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen_range:	370-429/822
Subcellular location:	Extracellular
Source:	KLH conjugated synthetic peptide derived from rat TrkB
Gene ID number:	4915
Swiss Prot:	Q16620
Tested applications:	FCM
Recommended dilutions:	FCM(1:20-100)
Crossreactivity:	Mouse, Rat, Human
Crossreactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background:	Alternatively can also bind NTF3/neurotrophin-3 which is less efficient in activating the receptor but regulates neuron survival through NTRK2, FRS2, FRS2, Hence, May also play a role in neutrophin-dependent calcium signaling in glial cells and mediate communication between neurons and glia, PLCG1 also leads to NF-Kappa-B activation and the transcription of genes involved in cell survival, Receptor for BDNF/brain-derived neurotrophic factor and NTF4/neurotrophin-4, Recruits, SH2B1, SH2B1, SH2B2 activates the GRB2-Ras-MAPK cascade that regulates for instance neuronal differentiation including neurite outgrowth, SH2B2 and PLCG1 that regulate distinct overlapping signaling cascades, Thereby, Through PLCG1 and the downstream protein kinase C-regulated pathways controls synaptic plasticity, Through SHC1, Through the same effectors controls the Ras-PI3 kinase-AKT1 signaling cascade that mainly regulates growth and survival, Upon ligand-binding, and synapse formation and plasticity, autophosphorylation and activation, differentiation, it is able to suppress anoikis, migration, phosphorylates and/or activates several downstream effectors including SHC1, plays a role in learning and memory by regulating both short term synaptic function and long-term potentiation, proliferation, the apoptosis resulting from loss of cell-matrix interactions, undergoes homodimerization, Receptor tyrosine kinase involved in the development and the maturation of the central and the peripheral nervous systems through regulation of neuron survival
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission:	480, 565nm/578nm
Synonyms:	BDNF/NT-3 growth factors receptor, GP145-TrkB, NTRK2, Neurotrophic tyrosine kinase receptor type 2, TrkB tyrosine kinase, Tropomyosin-related kinase B, trk-B, TRKB
Properties:	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target:	TrkB PE Conjugated
Short name:	PE Conjugated, TrkB Antibody
Technique:	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label:	PE
Alternative name:	peroxidase coupled, TrkB (Antibody to)
Alternative technique:	antibodies

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