| Long name: |
ALEXA FLUOR 488 Conjugated, GTP cyclohydrolase 1 Polyclonal Antibody |
| Also known as: |
Anti-GTP cyclohydrolase 1 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GTP cyclohydrolase 1 |
| Specificity: |
This is a highly specific antibody against GTP cyclohydrolase 1 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GTP-CH-1 |
| Gene ID Number: |
2643 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Animals can synthesize tetrahydrobiopterin in vivo from GTP through several enzymatic reactions, Tetrahydrobiopterin is an essential cofactor for 3 aromatic amino acid monooxygenases: phenylalanine, and tryptophan hydroxylases, the first and rate-limiting step in tetrahydrobiopterin (BH4) biosynthesis, tyrosine, 8-dihydroneopterin triphosphate, GTP cyclohydrolase I (also designated dopa-responsive dystonia) catalyzes the conversion of GTP to D-erythro-7 |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
GTPCH1 DYT5a |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the GTP cyclohydrolase 1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
GTP cyclohydrolase 1 |
| Short name: |
GTP cyclohydrolase 1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, GTP cyclohydrolase 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4193 |
| Gene: |
GCH1 |
More about : GCH1 |
| Long gene name: |
GTP cyclohydrolase 1 |
| Synonyms gene: |
GCH DYT5 DYT14 |
| Synonyms gene name: |
dystonia 14 |
| Synonyms name: |
dopa-responsive dystonia |
| Locus: |
14q22, 2 |
| Discovery year: |
1988-05-11 |
| GenBank acession: |
U19523 |
| Entrez gene record: |
2643 |
| Pubmed identfication: |
7874165 8695054 |
| Havana BLAST/BLAT: |
OTTHUMG00000029754 |
| Locus Specific Databases: |
BIOMDBdb: Database of Mutations Causing BH4 Deficiencies and other PND |