| Long name: |
Acinus Primary Polyclonal Antibody |
| Also known as: |
Acinus PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Acinus |
| Specificity: |
This is a highly specific antibody against Acinus |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Acinus |
| Gene ID number: |
22985 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
A new inducer of chromatin condensation was recently identified and designated Acinus (for apoptotic chromatin condensation inducer in the nucleus), Acinus S (583 amino acids) and Acinus S' (614 amino acids), Acinus also induces apoptotic chromatin condensation in cells, Acinus is cleaved by Caspase 3 and an additional unknown protease generating a small active peptide p17, Acinus is ubiquitously expressed, CCNF is triggered by the activation of members of the caspase family, Three different spliced forms of Acinus have been identified in human and mouse and designated Acinus L (1341 amino acids), and several novel proteins including AIF and CIDE, caspase activated DNase (CAD/DFF40), which causes chromatin condensation in vitro when it is added to purified nuclei, Chromatin condensation and nuclear fragmentation (CCNF) are the hallmarks of apoptosis |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
ACIN1, ACINU_HUMAN, ACN, Acinus, Apoptotic chromatin condensation inducer 1, Apoptotic chromatin condensation inducer in the nucleus, DKFZp667N107, KIAA0670, fSAP152, functional spliceosome-associated protein 152, ACIN 1 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Acinus |
| Short name: |
Acinus Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Acinus (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
17066 |
| Gene: |
ACIN1 |
More about : ACIN1 |
| Long gene name: |
apoptotic chromatin condensation inducer 1 |
| Synonyms gene: |
ACINUS |
| Synonyms gene name: |
apoptotic chromatin condensation inducer in the nucleus |
| Synonyms: |
KIAA0670 fSAP152 |
| Synonyms name: |
functional spliceosome-associated protein 152 |
| Locus: |
14q11, 2 |
| Discovery year: |
2003-01-14 |
| GenBank acession: |
AB014570 |
| Entrez gene record: |
22985 |
| Pubmed identfication: |
9734811 10490026 |
| RefSeq identity: |
NM_014977 |
| Classification: |
ASAP complex |
| Havana BLAST/BLAT: |
OTTHUMG00000028716 |