Caspase 8 Antibody, ALEXA FLUOR 350

Catalog number:	bs-0052R-A350 Buy Now
Price:	350 €
Supplier:	Bioss Primary Conjugated Antibodies
Product name:	Caspase 8 Antibody, ALEXA FLUOR 350
Quantity:	0.1ml
Related search:	caspase casp fluor antibody gene conjugated death disc deg

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Long name:	ALEXA FLUOR 350 Conjugated, Caspase 8 Polyclonal Antibody
Also known as:	Anti-Caspase 8 PAb ALEXA FLUOR 350
Category:	Conjugated Primary Antibodies
Conjugated with:	350, ALEXA FLUOR®
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	Caspase 8
Specificity:	This is a highly specific antibody against Caspase 8
Modification:	Unmodified
Modification Site:	None
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen range:	430-482/482
Subcellular location:	Cytoplasm
Source:	KLH conjugated synthetic peptide derived from mouse Caspase-8 subunit p10
Gene ID Number:	12370
Swiss Prot:	O89110
Tested applications:	IF(ICC), IF(IHC-P)
Recommended dilutions:	IF(ICC)(1:50-200), IF(IHC-P)(1:50-200)
Crossreactivity:	Mouse, Rat, Human
Cross-reactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen:	Ac-Asp-Glu-Val-Asp-|-AMC, Binding to the adapter molecule FADD recruits it to either receptor, CAP5 and CAP6) are likely retained in the DISC, CASP4, CASP6, CASP7, CASP9 and CASP1, Cleaves ADPRT, Cleaves and activates CASP3, Hydrolyzes the small-molecule substrate, Likely target for the cowpox virus CRMA death inhibitory protein, May participate in the GZMB apoptotic pathways, Proteolytic fragments of the N-terminal propeptide (termed CAP3, The active dimeric enzyme is then liberated from the DISC and free to activate downstream apoptotic proteases, The resulting aggregate called death-inducing signaling complex (DISC) performs CASP8 proteolytic activation, Most upstream protease of the activation cascade of caspases responsible for the TNFRSF6/FAS mediated and TNFRSF1A induced cell death
Purification:	Purified by Protein A
Storage conditions:	50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission:	343nm/442nm
Synonyms:	MCH5 MACH FLICE Casp-8
Properties:	ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation:	ALEXA FLUOR 350, Alexa Fluor
Gene target:	Caspase 8
Short name:	Caspase 8 Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Label:	ALEXA FLUOR 350
Alternative name:	ALEXA FLUOR 350, caspase 8 (Antibody to)
Alternative technique:	antibodies
Identity:	1509
Gene:	CASP8 | More about : CASP8
Long gene name:	caspase 8
Synonyms gene name:	apoptosis-related cysteine peptidase , apoptosis-related cysteine protease caspase 8, caspase 8
Locus:	2q33, 1
Discovery year:	1996-11-11
GenBank acession:	U60520
Entrez gene record:	841
Pubmed identfication:	8681376 8681377
RefSeq identity:	NM_001228
Classification:	Caspases Death effector domain containing Ripoptosome Death inducing signaling complex
Havana BLAST/BLAT:	OTTHUMG00000132821
Locus Specific Databases:	CASP8base: Mutation registry for Caspase 8 deficiency LRG_34

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