| Reacts with: |
Human |
| Source: |
proteins, Recombinants or rec |
| Description: |
Recombinant Human CASK is produced by our Mammalian expression system and the target gene encoding Met1-Tyr898 is expressed with a 6His tag at the C-terminus |
| Molecular Weight: |
103, 2 kD |
| UniProt number: |
O14936-4 |
| State of the product: |
Liquid |
| Shipping conditions: |
Dry Ice/ice packs |
| Formulation: |
150 mM sodium chloride, 2 um filtered solution of 20 mM PB, 4, Supplied as a 0, pH7 |
| Storage recommendations: |
-20°, Please minimize freeze-thaw cycles, stable for 6 months after receipt, C, Store at < |
| Reconstitution: |
Dissolve the lyophilized protein in ddH2O, Do not mix by vortex or pipetting, It is not recommended to reconstitute to a concentration less than 100 &mu, Please aliquot the reconstituted solution to minimize freeze-thaw cycles, Always centrifuge tubes before opening, g/ml |
| Purity: |
and determined by Polyacrylamide gel electrophoresis, Greater than 95% |
| Sequence of the amino acid: |
MADDDVLFEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICHMLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMAPEVVKREPYGKPVDVWGCGVILFILLSGCLPFYGTKERLFEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKLKGAVLAAVSSHKFNSFYGDPPEELPDFSEDPTSSGLLAAERAVSQVLDSLEEIHALTDCSEKDLDFLHSVFQDQHLHTLLDLYDKINTKSSPQIRNPPSDAVQRAKEVLEEISCYPENNDAKELKRILTQPHFMALLQTHDVVAHEVYSDEALRVTPPPTSPYLNGDSPESANGDMDMENVTRVRLVQFQKNTDEPMGITLKMNELNHCIVARIMHGGMIHRQGTLHVGDEIREINGISVANQTVEQLQKMLREMRGSITFKIVPSYRTQSSSCEDLPSTTQPKGRQIYVRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDDHNWWQGKLENSKNGTAGLIPSPELQEWRVACIAMEKTKQEQQASCTWFGKKKKQYKDKYLAKHNADLVTYEEVVKLPAFKRKTLVLLGAHGVGRRHIKNTLITKHPDRFAYPIPHTTRPPKKDEENGKNYYFVSHDQMMQDISNNEYLEYGSHEDAMYGTKLETIRKIHEQGLIAILDVEPQALKVLRTAEFAPFVVFIAAPTITPGLNEDESLQRLQKESDILQRTYAHYFDLTIINNEIDETIRHLEEAVELVCTAPQWVPVSWVYVDHHHHHH |
| Levels of endotoxin: |
11 IEU/ug, LAL test shows less than than 0 |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, Homo sapiens sapiens), Human proteins, humans , ssp |
| Group: |
recombinants |
| Gene target: |
CASK (C-6His), CaM Kinase |
| Short name: |
CASK (C-6His), Recombinant CaM Kinase |
| Technique: |
E, coli recombinant proteins are , novo advises they will be reconstituted in a buffer soluion or culture medium for cell culture, supplied as white sterile powder lyopillized, Recombinant, genetic recombinations , in Escherichia coli |
| Species: |
Humans, Human |
| Alternative name: |
calcium/calmodulin-dependent serine protein kinase (MAGUK family) (C-6His), sapiens CaM phosphorylation catalyst, recombinant H |
| Alternative technique: |
rec |
| Alternative to gene target: |
CAGH39 and CAMGUK and CMG and FGS4 and LIN2 and MICPCH and MRXSNA and TNRC8, CASK and IDBG-57627 and ENSG00000147044 and 8573, CASK and IDBG-637908 and ENSBTAG00000020136 and 404149, Cask and IDBG-133241 and ENSMUSG00000031012 and 12361, nuclei, this GO :0001953 and negative regulation of cell-matrix adhesion and biological process this GO :0004385 and guanylate kinase activity and molecular function this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005516 and calmodulin binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005604 and basement membrane and cellular component this GO :0005634 and nucleus and cellular component this GO :0005652 and nuclear lamina and cellular component this GO :0005730 and nucleolus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0007155 and cell adhesion and biological process this GO :0010839 and negative regulation of keratinocyte proliferation and biological process this GO :0015629 and actin cytoskeleton and cellular component this GO :0016020 and membrane and cellular component this GO :0016323 and basolateral plasma membrane and cellular component this GO :0016363 and nuclear matrix and cellular component this GO :0016772 and transferase activity, this GO :0004385 : guanylate kinase activity, this GO :0004385 : guanylate kinase activity and also this GO :0004672 : protein kinase activity and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0005515 : protein binding and also this GO :0005516 : calmodulin binding and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, this GO :0004672 : protein kinase activity, this GO :0004674 : protein serine/threonine kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0005515 : protein binding, this GO :0005516 : calmodulin binding, this GO :0005524 : ATP binding, this GO :0016772 : transferase activity, this GO :0042043 : neurexin family protein binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0042043 : neurexin family protein binding, transferring phosphorus-containing groups and molecular function this GO :0030198 and extracellular matrix organization and biological process this GO :0042043 and neurexin family protein binding and molecular function this GO :0042734 and presynaptic membrane and cellular component this GO :0045202 and synapse and cellular component this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046939 and nucleotide phosphorylation and biological process this GO :0060170 and ciliary membrane and cellular component this GO :0061045 and negative regulation of wound healing and biological process this GO :0070509 and calcium ion import and biological process this GO :0090280 and positive regulation of calcium ion import and biological process this GO :0090288 and negative regulation of cellular response to growth factor stimulus and biological process, calcium/calmodulin-dependent serine protein kinase (MAGUK family) |
| Identity: |
1497 |
| Gene: |
CASK |
More about : CASK |
| Long gene name: |
calcium/calmodulin dependent serine protein kinase |
| Synonyms gene: |
TNRC8 |
| Synonyms gene name: |
trinucleotide repeat containing 8 calcium/calmodulin-dependent serine protein kinase (MAGUK family) |
| Synonyms: |
LIN2 CAGH39 FGS4 |
| Locus: |
Xp11, 4 |
| Discovery year: |
1998-09-25 |
| GenBank acession: |
AF035582 |
| Entrez gene record: |
8573 |
| Pubmed identfication: |
9722958 |
| RefSeq identity: |
NM_003688 |
| Classification: |
Trinucleotide repeat containing Membrane associated guanylate kinases PDZ domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000021378 |
| Locus Specific Databases: |
Mental Retardation database |