| Reacts with: |
Human |
| Source: |
proteins, Recombinants or rec |
| Description: |
Recombinant Human Toll-Interacting Protein is produced by our E, coli expression system and the target gene encoding Ala2-Pro274 is expressed with a 6His tag at the C-terminus |
| Molecular Weight: |
3 kD, 31 |
| UniProt number: |
Q9H0E2 |
| State of the product: |
Freeze-dried |
| Shipping conditions: |
Ambient temperature |
| Formulation: |
150 mM sodium chloride, 5 mM EDTA, pH 7, 2, 2 um filtered solution of 20 mM PB, Lyophilized from a 0 |
| Storage recommendations: |
-20°, Aliquots of reconstituted samples are stable at less -20°, If kept at at room temperature, If kept at at room temperature, Reconstituted protein solution should be stored at 4-7°, it is stable for 3 weeks, it is stable for 3 weeks, C, C for 2-7 days, C for 3 months, Freeze-dried proteins should be stored frozen at < |
| Reconstitution: |
Dissolve the lyophilized protein in ddH2O, Do not mix by vortex or pipetting, It is not recommended to reconstitute to a concentration less than 100 &mu, Please aliquot the reconstituted solution to minimize freeze-thaw cycles, Always centrifuge tubes before opening, g/ml |
| Purity: |
and determined by Polyacrylamide gel electrophoresis, Greater than 95% |
| Sequence of the amino acid: |
ATTVSTQRGPVYIGELPQDFLRITPTQQQRQVQLDAQAAQQLQYGGAVGTVGRLNITVVQAKLAKNYGMTRMDPYCRLRLGYAVYETPTAHNGAKNPRWNKVIHCTVPPGVDSFYLEIFDERAFSMDDRIAWTHITIPESLRQGKVEDKWYSLSGRQGDDKEGMINLVMSYALLPAAMVMPPQPVVLMPTVYQQGVGYVPITGMPAVCSPGMVPVALPPAAVNAQPRCSEEDLKAIQDMFPNMDQEVIRSVLEAQRGNKDAAINSLLQMGEEPVEHHHHHH |
| Levels of endotoxin: |
11 IEU/ug, LAL test shows less than than 0 |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine,  , (Homo sapiens, Homo sapiens sapiens), Human proteins, humans , ssp |
| Group: |
recombinants |
| Gene target: |
TOLLIP (C-6His), Toll-Interacting Protein |
| Short name: |
TOLLIP (C-6His), Recombinant Toll-Interacting Protein |
| Technique: |
E, coli recombinant proteins are , novo advises they will be reconstituted in a buffer soluion or culture medium for cell culture, supplied as white sterile powder lyopillized, Recombinant, genetic recombinations , in Escherichia coli |
| Species: |
Humans, Human |
| Alternative name: |
sapiens Toll-Interacting Protein, toll interacting protein (C-6His), recombinant H |
| Alternative technique: |
rec |
| Alternative to gene target: |
TOLLIP and IDBG-19140 and ENSG00000078902 and 54472, TOLLIP and IDBG-645625 and ENSBTAG00000008237 and 539480, Tollip and IDBG-212409 and ENSMUSG00000025139 and 54473, Type I receptor binding, Type I receptor binding and also this GO :0005515 : protein binding and also this GO :0019900 : kinase binding and also this GO :0031624 : ubiquitin conjugating enzyme binding and also this GO :0031625 : ubiquitin protein ligase binding and also this GO :0032183 : SUMO binding and also this GO :0035325 : Toll-like receptor binding, Type I receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006954 and inflammatory response and biological process this GO :0007165 and signal transduction and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0016310 and phosphorylation and biological process this GO :0016604 and nuclear body and cellular component this GO :0019900 and kinase binding and molecular function this GO :0030855 and epithelial cell differentiation and biological process this GO :0031624 and ubiquitin conjugating enzyme binding and molecular function this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0032183 and SUMO binding and molecular function this GO :0033235 and positive regulation of protein sumoylation and biological process this GO :0035325 and Toll-like receptor binding and molecular function this GO :0035556 and intracellular signal transduction and biological process this GO :0036010 and protein localization to endosome and biological process this GO :0045087 and innate immune response and biological process this GO :0045092 and interleukin-18 receptor complex and cellular component this GO :0045321 and leukocyte activation and biological process this GO :0045323 and interleukin-1 receptor complex and cellular component this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0070062 and extracellular vesicular exosome and cellular component, interleukin-1, nuclei, this GO :0004871 and signal transducer activity and molecular function this GO :0005150 and interleukin-1, this GO :0004871 : signal transducer activity, this GO :0004871 : signal transducer activity and also this GO :0005150 : interleukin-1, this GO :0005150 : interleukin-1, this GO :0005515 : protein binding, this GO :0019900 : kinase binding, this GO :0031624 : ubiquitin conjugating enzyme binding, this GO :0031625 : ubiquitin protein ligase binding, this GO :0032183 : SUMO binding, this GO :0035325 : Toll-like receptor binding, toll interacting protein |
| Identity: |
16476 |
| Gene: |
TOLLIP |
More about : TOLLIP |
| Long gene name: |
toll interacting protein |
| Synonyms: |
IL-1RAcPIP |
| Locus: |
11p15, 5 |
| Discovery year: |
2003-03-13 |
| GenBank acession: |
AJ242972 |
| Entrez gene record: |
54472 |
| Pubmed identfication: |
9426216 10854325 |
| RefSeq identity: |
NM_019009 |
| Classification: |
C2 domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000133333 |