| Reacts with: |
Human |
| Source: |
proteins, Recombinants or rec |
| Description: |
Recombinant Human Protein C is produced by our Mammalian expression system and the target gene encoding Thr19-Pro461 is expressed with a 6His tag at the C-terminus |
| Molecular Weight: |
1 kD, 51 |
| UniProt number: |
P04070 |
| State of the product: |
Liquid |
| Shipping conditions: |
Dry ice/ice packs |
| Formulation: |
10%Glycerol, 150 mM sodium chloride, 2 um filtered solution of 20 mM TrisHCl, 5, Supplied as a 0, pH7 |
| Storage recommendations: |
-20°, Please minimize freeze-thaw cycles, stable for 6 months after receipt, C, Store at < |
| Reconstitution: |
Dissolve the lyophilized protein in ddH2O, Do not mix by vortex or pipetting, It is not recommended to reconstitute to a concentration less than 100 &mu, Please aliquot the reconstituted solution to minimize freeze-thaw cycles, Always centrifuge tubes before opening, g/ml |
| Purity: |
and determined by Polyacrylamide gel electrophoresis, Greater than 95% |
| Sequence of the amino acid: |
TPAPLDSVFSSSERAHQVLRIRKRANSFLEELRHSSLERECIEEICDFEEAKEIFQNVDDTLAFWSKHVDGDQCLVLPLEHPCASLCCGHGTCIDGIGSFSCDCRSGWEGRFCQREVSFLNCSLDNGGCTHYCLEEVGWRRCSCAPGYKLGDDLLQCHPAVKFPCGRPWKRMEKKRSHLKRDTEDQEDQVDPRLIDGKMTRRGDSPWQVVLLDSKKKLACGAVLIHPSWVLTAAHCMDESKKLLVRLGEYDLRRWEKWELDLDIKEVFVHPNYSKSTTDNDIALLHLAQPATLSQTIVPICLPDSGLAERELNQAGQETLVTGWGYHSSREKEAKRNRTFVLNFIKIPVVPHNECSEVMSNMVSENMLCAGILGDRQDACEGDSGGPMVASFHGTWFLVGLVSWGEGCGLLHNYGVYTKVSRYLDWIHGHIRDKEAPQKSWAPLEHHHHHH |
| Levels of endotoxin: |
11 IEU/ug, LAL test shows less than than 0 |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, Homo sapiens sapiens), Human proteins, humans , ssp |
| Group: |
recombinants |
| Gene target: |
PROC (C-6His), Vitamin K-Dependent Protein C |
| Short name: |
PROC (C-6His), Recombinant Vitamin K-Dependent Protein C |
| Technique: |
E, coli recombinant proteins are , novo advises they will be reconstituted in a buffer soluion or culture medium for cell culture, supplied as white sterile powder lyopillized, Recombinant, genetic recombinations , in Escherichia coli |
| Species: |
Humans, Human |
| Alternative name: |
protein C (inactivator on coagulation factors Va and VIIIa) (C-6His), sapiens Vitamin K-Dependent Protein C, recombinant H |
| Alternative technique: |
rec |
| Alternative to gene target: |
APC and PC and PROC1 and THPH3 and THPH4, Extracellular, PROC and IDBG-639221 and ENSBTAG00000003950 and 281428, PROC and IDBG-69078 and ENSG00000115718 and 5624, Proc and IDBG-133467 and ENSMUSG00000024386 and 19123, peptidase activity, this GO :0003824 and catalytic activity and molecular function this GO :0004252 and serine-type endopeptidase activity and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005788 and endoplasmic reticulum lumen and cellular component this GO :0005796 and this GO lgi lumen and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006508 and proteolysis and biological process this GO :0007596 and blood coagulation and biological process this GO :0008233 and peptidase activity and molecular function this GO :0017187 and peptidyl-glutamic acid carboxylation and biological process this GO :0030195 and negative regulation of blood coagulation and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043687 and post-translational protein modification and biological process this GO :0044267 and cellular protein metabolic process and biological process this GO :0050900 and leukocyte migration and biological process, this GO :0003824 : catalytic activity, this GO :0003824 : catalytic activity and also this GO :0004252 : serine-type endopeptidase activity and also this GO :0005509 : calcium ion binding and also this GO :0005515 : protein binding and also this GO :0008233 : peptidase activity, this GO :0004252 : serine-type endopeptidase activity, this GO :0005509 : calcium ion binding, this GO :0005515 : protein binding, this GO :0008233 : peptidase activity, protein C (inactivator of coagulation factors Va and VIIIa) |
| Identity: |
9451 |
| Gene: |
PROC |
More about : PROC |
| Long gene name: |
inactivator of coagulation factors Va and VIIIa , protein C |
| Synonyms gene name: |
protein C (inactivator of coagulation factors Va and VIIIa) |
| Synonyms name: |
prepro-protein C |
| Locus: |
2q14, 3 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
X02750 |
| Entrez gene record: |
5624 |
| Pubmed identfication: |
2991887 2437584 |
| RefSeq identity: |
NM_000312 |
| Classification: |
Endogenous ligands Gla domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000131528 |
| Locus Specific Databases: |
3d Protein C Mutations Database LRG_599 |