| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
STT3A |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
Western blot: 1:1000-2000 |
| Intented use: |
This STT3A antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
3703 |
| Uniprot #: |
P46977 |
| Purity: |
Antigen affinity |
| Description: |
N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER), SST3A seems to be involved in complex substrate specificity, STT3A is present in the majority of OST complexes and mediates cotranslational N-glycosylation of most sites on target proteins, while STT3B-containing complexes are required for efficient cotranslational glycosylation and mediate glycosylation of sites that have been skipped by STT3A, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A is the catalytic subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains |
| Immunogen: |
A portion of amino acids 476-507 from the human protein was used as the immunogen for the STT3A antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the STT3A antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
STT3A |
| Short name: |
STT3A Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
STT3A (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6172 |
| Gene: |
STT3A |
More about : STT3A |
| Long gene name: |
STT3A, catalytic subunit of the oligosaccharyltransferase complex |
| Synonyms gene: |
ITM1 |
| Synonyms gene name: |
cerevisiae) , homolog A (S, integral membrane protein 1 STT3, subunit of the oligosaccharyltransferase complex |
| Synonyms: |
TMC MGC9042 STT3-A |
| Synonyms name: |
dolichyl-diphosphooligosaccharide protein glycotransferase |
| Locus: |
11q24, 2 |
| Discovery year: |
1996-08-01 |
| GenBank acession: |
BC020965 |
| Entrez gene record: |
3703 |
| Pubmed identfication: |
8941377 8634329 10234787 |
| RefSeq identity: |
NM_152713 |
| Classification: |
Oligosaccharyltransferase complex subunits STT3 oligosaccharyltransferase catalytic subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000165852 |