| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
ROBO1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
Western blot: 1:1000-1:2000 |
| Intented use: |
This ROBO1 antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
6091 |
| Uniprot #: |
Q9Y6N7 |
| Purity: |
Antigen affinity |
| Description: |
In axon growth cones, May be required for lung development, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development, the silencing of the attractive effect of NTN1 by SLIT2 may require the formation of a ROBO1-DCC complex, Roundabout homolog 1 is the receptor for SLIT1 and SLIT2 which are thought to act as molecular guidance cue in cellular migration |
| Immunogen: |
A portion of amino acids 1097-1130 from the human protein was used as the immunogen for the ROBO1 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the ROBO1 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
ROBO1 |
| Short name: |
ROBO1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
axon guidance receptor, homolog 1 (Drosophila) (Antibody to), roundabout |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Cell surfaces, DUTT1 and SAX3, ROBO1 and IDBG-45469 and ENSG00000169855 and 6091, ROBO1 and IDBG-630648 and ENSBTAG00000009851 and 536815, Robo1 and IDBG-171072 and ENSMUSG00000022883 and 19876, axon guidance receptor, homolog 1 (Drosophila), protein heterodimerization activity, this GO :0002042 and cell migration involved in sprouting angiogenesis and biological process this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006919 and activation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0007155 and cell adhesion and biological process this GO :0007156 and homophilic cell adhesion and biological process this GO :0007399 and nervous system development and biological process this GO :0007411 and axon guidance and biological process this GO :0008046 and axon guidance receptor activity and molecular function this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0009986 and cell surface and cellular component this GO :0016199 and axon midline choice point recognition and biological process this GO :0021836 and chemorepulsion involved in postnatal olfactory bulb interneuron migration and biological process this GO :0030275 and LRR domain binding and molecular function this GO :0030673 and axolemma and cellular component this GO :0033600 and negative regulation of mammary gland epithelial cell proliferation and biological process this GO :0035385 and Roundabout signaling pathway and biological process this GO :0042802 and identical protein binding and molecular function this GO :0046982 and protein heterodimerization activity and molecular function this GO :0050772 and positive regulation of axonogenesis and biological process this GO :0050925 and negative regulation of negative chemotaxis and biological process this GO :0060763 and mammary duct terminal end bud growth and biological process this GO :0070100 and negative regulation of chemokine-mediated signaling pathway and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0008046 : axon guidance receptor activity and also this GO :0030275 : LRR domain binding and also this GO :0042802 : identical protein binding and also this GO :0046982 : protein heterodimerization activity, this GO :0008046 : axon guidance receptor activity, this GO :0030275 : LRR domain binding, this GO :0042802 : identical protein binding, this GO :0046982 : protein heterodimerization activity, roundabout |
| Identity: |
10249 |
| Gene: |
ROBO1 |
More about : ROBO1 |
| Long gene name: |
roundabout guidance receptor 1 |
| Synonyms gene name: |
Drosophila) homolog 1 roundabout, axon guidance receptor, homolog 1 (Drosophila) , roundabout (axon guidance receptor |
| Synonyms: |
DUTT1 FLJ21882 SAX3 |
| Locus: |
3p12, 3 |
| Discovery year: |
1998-03-26 |
| GenBank acession: |
AF040990 |
| Entrez gene record: |
6091 |
| Pubmed identfication: |
9458045 9608531 |
| RefSeq identity: |
NM_002941 |
| Classification: |
Fibronectin type III domain containing I-set domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000158843 |