| Long name: |
Robo1/2 Primary Polyclonal Antibody |
| Also known as: |
Robo1/2 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Robo1/2 |
| Specificity: |
This is a highly specific antibody against Robo1/2 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
80-130/1651 |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Robo1/2 |
| Gene ID number: |
6091, 6092 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
In the vertebrate spinal cord, Non-crossing axons express high levels of Robo, One such gatekeeper, Robo, Robo acts as a receptor for the repellent Slit and functions in a cell-autonomous fashion (1-3), Robo1 and Robo2 are two human homologs of the Drosophila protein Roundabout (2-4), Robo1 is also homologous to the C, These cells may act as gatekeepers to prevent axons from crossing the midline and to induce a switch in growth cone responsiveness to guidance cues beyond the gateway (1), elegans, elegans gene sax3, have a number of roles in directing growth cone behavior (1), is an axon guidance receptor that defines a novel subfamily of Ig superfamily proteins that are conserved from fruit flies to mammals (2, midline cells produce guidance cues such as nectins and slit, respectively (1), the insect ventral nerve cord and in C, whereas Robo2 is homologous to the zebrafish gene astray (5, whereas crossing axons express low levels of Robo before reaching the midline and high levels after they cross (1), which act as attractants and repellents, which separates the left and right halves of the CNS, 3), 6), Specialized cells at the midline |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
DUTT 1, DUTT1, Deleted in U twenty twenty, FLJ21882, H Robo 1, H-Robo-1, ROBO1_HUMAN, Robo 1, Robo 2, Robo1, Roundabout 1, Roundabout 2, Roundabout axon guidance receptor homolog 1, Roundabout axon guidance receptor homolog 2, Roundabout homolog 1, Roundabout homolog1 precurser, Roundabout1, SAX 3, SAX3, hRobo 1, Axon guidance receptor |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Robo1/2 |
| Short name: |
Robo1/2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
axon guidance receptor, homolog 1 (Drosophila)/2 (Antibody to), roundabout |
| Alternative technique: |
antibodies |