| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
EFS / Embryonal Fyn-associated substrate |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
Western blot: 1:1000-1:2000 |
| Intented use: |
This EFS antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
10278 |
| Uniprot #: |
O43281 |
| Purity: |
Antigen affinity |
| Description: |
Interacts with the SH3 domain of FYN and with CRK, May serve as an activator of SRC and a downstream effector, SRC, and YES (By similarity), Embryonal Fyn-associated substrate is a docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion |
| Immunogen: |
A portion of amino acids 367-399 from the human protein was used as the immunogen for the EFS antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the EFS antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
EFS / Embryonal Fyn-associated substrate |
| Short name: |
EFS Antibody / Embryonal Fyn-associated substrate |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
FGR, FGR, YES-associated substrate, YES-associated substrate (Antibody to) / Embryonal FYN oncogene related to v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian), embryonal FYN oncogene related to v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CAS3 and CASS3 and EFS1 and EFS2 and HEFS and SIN, Cytoplasm, EFS and IDBG-3201 and ENSG00000100842 and 10278, EFS and IDBG-645821 and ENSBTAG00000038733 and 508559, Efs and IDBG-162509 and ENSMUSG00000022203 and 13644, protein domain specific binding, this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0007155 and cell adhesion and biological process this GO :0017124 and SH3 domain binding and molecular function this GO :0019904 and protein domain specific binding and molecular function this GO :0035556 and intracellular signal transduction and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0017124 : SH3 domain binding and also this GO :0019904 : protein domain specific binding, this GO :0017124 : SH3 domain binding, this GO :0019904 : protein domain specific binding, embryonal Fyn-associated substrate |
| Identity: |
16898 |
| Gene: |
EFS |
More about : EFS |
| Long gene name: |
embryonal Fyn-associated substrate |
| Synonyms: |
EFS2 EFS1 HEFS SIN CASS3 |
| Synonyms name: |
Cas scaffolding protein family member 3 |
| Locus: |
14q11, 2 |
| Discovery year: |
2003-01-29 |
| GenBank acession: |
AB001466 |
| Entrez gene record: |
10278 |
| Pubmed identfication: |
9349509 |
| Classification: |
Cas scaffolding proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000028741 |