| Also known as: |
SYN / FYN |
| Other names: |
FGR, FYN oncogene related to SRC, FYN proto-oncogene, OKT3-induced calcium influx regulator, Proto-oncogene Syn, Proto-oncogene c-Fyn, SLK, Src family tyrosine kinase, Src-like kinase, Tyrosine-protein kinase Fyn, YES, c-syn protooncogene, p59-Fyn, proto-oncogene Syn, proto-oncogene c-Fyn, src-like kinase, src/yes-related novel, tyrosine kinase p59fyn(T), tyrosine-protein kinase Fyn, tyrosine-protein kinase Fyn isoform a |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
SYN |
| Gene name synonims: |
FYN |
| Other gene names: |
FYN, SLK, SLK, SYN, p59-FYN, FYN |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG |
| Clone: |
FYN-59 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, Mouse (Mus musculus), the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Partial recombinant human Fyn (aa 7-176) expressed in E coli |
| Purification method: |
Affinity Purified |
| Form/Appearance: |
0, pH 7, 09% sodium azide at 0, 2, 5 mg/ml, Phosphate-buffered solution |
| Storage and shipping: |
Freezing of the antibody is not recommended, Store the antibody at +4 degrees Celsius |
| Tested applications:: |
Immunoprecipitation (IP), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
2 light chains, Each murine monoclonal anibody has his own affinity specific for the clone, For storage sodium azide is added or you can call us to request azide free antibody preparations, IgG, Monoclonals of this antigen are available in different clones, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, The IgG antibody has 2 , There are 2 heavy chains, These will need colder storage temperatures, They represent 70% or more of , This antibody can be antigen purified or protein A or G purified, goat polyclonal antibodies , mouse monoclonal H&, Immunoglobulin gamma, L chain clones or rabbit, antibodies, antigen , binding sites, have 4 parts, serum |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ FYN-59] SYN / FYN |
| Short name: |
Mouse Monoclonal [clone FYN-59] (IgG) SYN / FYN Antibody |
| Technique: |
IgGs, Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
FGR, FGR, YES (Antibody to), YES-59] (Immunoglobulin G) to H, sapiens SYN / FYN oncogene related to v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian), Mouse monoclonal [clonality FYN oncogene related to v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
FGR, FYN and IDBG-631420 and ENSBTAG00000011851 and 527263, FYN and IDBG-95463 and ENSG00000010810 and 102724705, Fyn and IDBG-144629 and ENSMUSG00000019843 and 14360, YES, nuclei, p59-FYN and SLK and SYN, this GO :0001664 and G-protein coupled receptor binding and molecular function this GO :0001764 and neuron migration and biological process this GO :0001948 and glycoprotein binding and molecular function this GO :0004672 and protein kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004715 and non-membrane spanning protein tyrosine kinase activity and molecular function this GO :0005102 and receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005768 and endosome and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006816 and calcium ion transport and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0007411 and axon guidance and biological process this GO :0007596 and blood coagulation and biological process this GO :0007612 and learning and biological process this GO :0007631 and feeding behavior and biological process this GO :0008360 and regulation of cell shape and biological process this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0010629 and negative regulation of gene expression and biological process this GO :0010976 and positive regulation of neuron projection development and biological process this GO :0014068 and positive regulation of phosphatidylinositol 3-kinase signaling and biological process this GO :0014069 and postsynaptic density and cellular component this GO :0015631 and tubulin binding and molecular function this GO :0016020 and membrane and cellular component this GO :0016032 and viral process and biological process this GO :0016772 and transferase activity, this GO :0001664 : G-protein coupled receptor binding, this GO :0001664 : G-protein coupled receptor binding and also this GO :0001948 : glycoprotein binding and also this GO :0004672 : protein kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0004715 : non-membrane spanning protein tyrosine kinase activity and also this GO :0005102 : receptor binding and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0015631 : tubulin binding and also this GO :0016772 : transferase activity, this GO :0001948 : glycoprotein binding, this GO :0004672 : protein kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0004715 : non-membrane spanning protein tyrosine kinase activity, this GO :0005102 : receptor binding, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0015631 : tubulin binding, this GO :0016772 : transferase activity, this GO :0032403 : protein complex binding, this GO :0042608 : T cell receptor binding, this GO :0042609 : CD4 receptor binding, this GO :0042610 : CD8 receptor binding, this GO :0043548 : phosphatidylinositol 3-kinase binding, this GO :0044325 : ion channel binding, this GO :0046872 : metal ion binding, this GO :0046875 : ephrin receptor binding, this GO :0051428 : peptide hormone receptor binding, this GO :0070851 : growth factor receptor binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0032403 : protein complex binding and also this GO :0042608 : T cell receptor binding and also this GO :0042609 : CD4 receptor binding and also this GO :0042610 : CD8 receptor binding and also this GO :0043548 : phosphatidylinositol 3-kinase binding and also this GO :0044325 : ion channel binding and also this GO :0046872 : metal ion binding and also this GO :0046875 : ephrin receptor binding and also this GO :0051428 : peptide hormone receptor binding and also this GO :0070851 : growth factor receptor binding, transferring phosphorus-containing groups and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0030168 and platelet activation and biological process this GO :0030900 and forebrain development and biological process this GO :0031295 and T cell costimulation and biological process this GO :0032403 and protein complex binding and molecular function this GO :0035556 and intracellular signal transduction and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0038096 and Fc-gamma receptor signaling pathway involved in pha this GO cytosis and biological process this GO :0042177 and negative regulation of protein catabolic process and biological process this GO :0042493 and response to drug and biological process this GO :0042608 and T cell receptor binding and molecular function this GO :0042609 and CD4 receptor binding and molecular function this GO :0042610 and CD8 receptor binding and molecular function this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0043548 and phosphatidylinositol 3-kinase binding and molecular function this GO :0044325 and ion channel binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045121 and membrane raft and cellular component this GO :0045471 and response to ethanol and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0046872 and metal ion binding and molecular function this GO :0046875 and ephrin receptor binding and molecular function this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048015 and phosphatidylinositol-mediated signaling and biological process this GO :0048813 and dendrite morphogenesis and biological process this GO :0050690 and regulation of defense response to virus by virus and biological process this GO :0050798 and activated T cell proliferation and biological process this GO :0050852 and T cell receptor signaling pathway and biological process this GO :0050900 and leukocyte migration and biological process this GO :0050966 and detection of mechanical stimulus involved in sensory perception of pain and biological process this GO :0051428 and peptide hormone receptor binding and molecular function this GO :0070851 and growth factor receptor binding and molecular function this GO :0071363 and cellular response to growth factor stimulus and biological process this GO :0071375 and cellular response to peptide hormone stimulus and biological process this GO :1900182 and positive regulation of protein localization to nucleus and biological process this GO :2001240 and negative regulation of extrinsic apoptotic signaling pathway in absence of ligand and biological process, 2534, FYN oncogene related to SRC |
| Identity: |
4037 |
| Gene: |
FYN |
More about : FYN |
| Long gene name: |
FYN proto-oncogene, Src family tyrosine kinase |
| Synonyms gene name: |
FGR, FYN oncogene related to SRC, YES |
| Synonyms: |
SYN SLK MGC45350 |
| Locus: |
6q21 |
| Discovery year: |
1988-08-19 |
| GenBank acession: |
AK056699 |
| Entrez gene record: |
2534 |
| Pubmed identfication: |
3526330 |
| Classification: |
SH2 domain containing Src family tyrosine kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000016305 |