| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
TRPV6 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
Western blot: 1:1000 |
| Notes: |
Titration of the TRPV6 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This TRPV6 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q9H1D0 |
| Purity: |
Antigen affinity |
| Description: |
Heteromeric assembly with TRPV5 seems to modify channel properties, In vitro, Inactivation includes both, TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating (By similarity), The channel is activated by low internal calcium level, a rapid Ca(2+)-dependent and a slower Ca(2+)-calmodulin- dependent mechanism, and the current exhibits an inward rectification, including Ca(2+) reabsorption in intestine, is slowly inhibited by Mg(2+) in a voltage-independent manner, probably including intracellular calcium store depletion, the latter may be regulated by phosphorylation, Calcium selective cation channel probably involved in Ca(2+) uptake in various tissues |
| Immunogen: |
This TRPV6 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 352-385 amino acids from the Central region of human TRPV6 |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the TRPV6 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
TRPV6 |
| Short name: |
TRPV6 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
member 6 (Antibody to), subfamily V, transient receptor potential cation channel |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Plasma membranes, TRPV6 and IDBG-45160 and ENSG00000165125 and 55503, TRPV6 and IDBG-636798 and ENSBTAG00000024219 and 614878, Trpv6 and IDBG-140883 and ENSMUSG00000029868 and 64177, calmodulin binding, member 6, subfamily V, this GO :0005216 and ion channel activity and molecular function this GO :0005262 and calcium channel activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005516 and calmodulin binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006811 and ion transport and biological process this GO :0006816 and calcium ion transport and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0017158 and regulation of calcium ion-dependent exocytosis and biological process this GO :0034220 and ion transmembrane transport and biological process this GO :0055085 and transmembrane transport and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070588 and calcium ion transmembrane transport and biological process, this GO :0005216 : ion channel activity, this GO :0005216 : ion channel activity and also this GO :0005262 : calcium channel activity and also this GO :0005515 : protein binding and also this GO :0005516 : calmodulin binding, this GO :0005262 : calcium channel activity, this GO :0005515 : protein binding, this GO :0005516 : calmodulin binding, transient receptor potential cation channel |
| Identity: |
14006 |
| Gene: |
TRPV6 |
More about : TRPV6 |
| Long gene name: |
transient receptor potential cation channel subfamily V member 6 |
| Synonyms gene: |
ECAC2 |
| Synonyms gene name: |
epithelial calcium channel 2 transient receptor potential cation channel, member 6 , subfamily V |
| Synonyms: |
CaT1 |
| Locus: |
7q34 |
| Discovery year: |
2000-11-24 |
| GenBank acession: |
AJ277909 |
| Entrez gene record: |
55503 |
| Pubmed identfication: |
11097838 11549322 16382100 16717058 |
| RefSeq identity: |
NM_014274 |
| Classification: |
Ankyrin repeat domain containing Transient receptor potential cation channels |
| Havana BLAST/BLAT: |
OTTHUMG00000157158 |