| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
TRPV6 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the TRPV6 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This TRPV6 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q9H1D0 |
| Purity: |
Antigen affinity |
| Description: |
CAT1 or CATL, Functional analysis by Peng et al, Peng et al, Peng et al, TRPV6 is a member of the Transient receptor potential (TRP) family of membrane proteins, They concluded that TRPV5 and TRPV6 are calcium-selective channels and share a common ancestral gene, Using FISH, a membrane calcium channel which is responsible for the first step in calcium absorption in the intestine, also known as ECAC2, and hydrogen, calcium influx was higher at alkaline rather than acidic pH, chloride, however, (2000) determined that TRPV6 mediates calcium uptake independent of sodium, (2000) mapped the gene to chromosome 7q33-q34, (2001) indicated that TRPV5 mediates greater calcium uptake than TRPV6, Transient Receptor Potential Cation Channel Subfamily V Member 6 |
| Immunogen: |
Amino acids 18-37 (KFCRWFQRRESWAQSRDEQN-human) were used as the immunogen for this TRPV6 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the TRPV6 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
TRPV6 |
| Short name: |
TRPV6 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
member 6 (Antibody to), subfamily V, transient receptor potential cation channel |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Plasma membranes, TRPV6 and IDBG-45160 and ENSG00000165125 and 55503, TRPV6 and IDBG-636798 and ENSBTAG00000024219 and 614878, Trpv6 and IDBG-140883 and ENSMUSG00000029868 and 64177, calmodulin binding, member 6, subfamily V, this GO :0005216 and ion channel activity and molecular function this GO :0005262 and calcium channel activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005516 and calmodulin binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006811 and ion transport and biological process this GO :0006816 and calcium ion transport and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0017158 and regulation of calcium ion-dependent exocytosis and biological process this GO :0034220 and ion transmembrane transport and biological process this GO :0055085 and transmembrane transport and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070588 and calcium ion transmembrane transport and biological process, this GO :0005216 : ion channel activity, this GO :0005216 : ion channel activity and also this GO :0005262 : calcium channel activity and also this GO :0005515 : protein binding and also this GO :0005516 : calmodulin binding, this GO :0005262 : calcium channel activity, this GO :0005515 : protein binding, this GO :0005516 : calmodulin binding, transient receptor potential cation channel |
| Identity: |
14006 |
| Gene: |
TRPV6 |
More about : TRPV6 |
| Long gene name: |
transient receptor potential cation channel subfamily V member 6 |
| Synonyms gene: |
ECAC2 |
| Synonyms gene name: |
epithelial calcium channel 2 transient receptor potential cation channel, member 6 , subfamily V |
| Synonyms: |
CaT1 |
| Locus: |
7q34 |
| Discovery year: |
2000-11-24 |
| GenBank acession: |
AJ277909 |
| Entrez gene record: |
55503 |
| Pubmed identfication: |
11097838 11549322 16382100 16717058 |
| RefSeq identity: |
NM_014274 |
| Classification: |
Ankyrin repeat domain containing Transient receptor potential cation channels |
| Havana BLAST/BLAT: |
OTTHUMG00000157158 |