| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Plau), Urokinase (UPA |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, FACS, IF, IHC, WB |
| Recommended dilutions: |
Flow Cytometry: 1:10-1:50, IHC (Paraffin): 1:10-1:50, Immunofluorescence: 1:10-1:50, Western blot: 1:1000 |
| Notes: |
Titration of the UPA antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This UPA antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P00749 |
| Purity: |
Purified |
| Description: |
A and B, Cleavage occurs after residue 155 in the low molecular mass form to yield a short A1 chain, Each consists of two chains, PLAU contains 1 EGF-like domain and 1 kringle domain, PLAU specifically cleaves the Arg-|-Val bond in plasminogen to form plasmin, Structurally, The high molecular mass form contains a long chain A, The protein is found in high and low molecular mass forms, The protein is used in Pulmonary Embolism (PE) to initiates fibrinolysis, a member of the peptidase family S1, is a potent plasminogen activator and is clinically used for therapy of thrombolytic disorders, PLAU |
| Immunogen: |
A portion of amino acids 396-426 from the human protein was used as the immunogen for this UPA antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the UPA antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Plau), Urokinase (UPA |
| Short name: |
Plau), Urokinase Antibody (UPA |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
plasminogen activator, urokinase), Urokinase (Antibody to) (UPA |
| Alternative technique: |
antibodies |
| Identity: |
9052 |
| Gene: |
PLAU |
More about : PLAU |
| Long gene name: |
plasminogen activator, urokinase |
| Synonyms: |
URK UPA |
| Locus: |
10q22, 2 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
BC013575 |
| Entrez gene record: |
5328 |
| Pubmed identfication: |
2415429 |
| RefSeq identity: |
NM_002658 |
| Havana BLAST/BLAT: |
OTTHUMG00000018494 |
| Locus Specific Databases: |
LRG_593 |