| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
PAK5 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, IHC, WB |
| Recommended dilutions: |
IHC (Paraffin): 1:10-1:50, Western blot: 1:1000 |
| Notes: |
Titration of the PAK5 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This PAK5 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q9P286 |
| Purity: |
Purified |
| Description: |
It is capable of promoting neurite outgrowth, PAK family members are known to be effectors of Rac/Cdc42 GTPases, The subcellular localization of this kinase is tightly regulated during cell cycle progression, This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, This kinase is associated with microtubule networks and induces microtubule stabilization, This kinase is predominantly expressed in brain, and cell survival signaling, and has been shown to bind CDC42 in the presence of GTP, and thus may play a role in neurite development, proliferation, which have been implicated in the regulation of cytoskeletal dynamics, PAK5 is a member of the PAK family of Ser/Thr protein kinases |
| Immunogen: |
A portion of amino acids 168-198 from the human protein was used as the immunogen for this PAK5 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the PAK5 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
PAK5 |
| Short name: |
PAK5 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
PAK5 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
16061 |
| Gene: |
PAK6 |
More about : PAK6 |
| Long gene name: |
p21 (RAC1) activated kinase 6 |
| Synonyms gene name: |
p21(CDKN1A)-activated kinase 6 p21 protein (Cdc42/Rac)-activated kinase 6 |
| Synonyms: |
PAK5 |
| Locus: |
15q15, 1 |
| Discovery year: |
2001-07-12 |
| GenBank acession: |
AF276893 |
| Entrez gene record: |
56924 |
| Pubmed identfication: |
11278661 |
| Havana BLAST/BLAT: |
OTTHUMG00000129921 |