| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
BACE1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, IHC, WB |
| Recommended dilutions: |
IHC (Paraffin): 1:10-1:50, Western blot: 1:1000 |
| Notes: |
Titration of the BACE1 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This BACE1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P56817 |
| Purity: |
Purified |
| Description: |
Cleaves at the N-terminus of the A-beta peptide sequence, [UniProt], and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, Responsible for the proteolytic processing of the amyloid precursor protein (APP) |
| Immunogen: |
A portion of amino acids 38-70 from the human protein was used as the immunogen for this BACE1 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot the BACE1 antibody and store frozen at -20 deg, Store at 4oC for up to one month |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
BACE1 |
| Short name: |
BACE1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
BACE1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
933 |
| Gene: |
BACE1 |
More about : BACE1 |
| Long gene name: |
beta-secretase 1 |
| Synonyms gene: |
BACE |
| Synonyms gene name: |
beta-site APP-cleaving enzyme beta-site APP-cleaving enzyme 1 |
| Locus: |
11q23, 3 |
| Discovery year: |
1999-10-29 |
| GenBank acession: |
AF190725 |
| Entrez gene record: |
23621 |
| Pubmed identfication: |
10531052 |
| Havana BLAST/BLAT: |
OTTHUMG00000160636 |