| Long name: |
BACE1 Primary Polyclonal Antibody |
| Also known as: |
BACE1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
BACE1 |
| Specificity: |
This is a highly specific antibody against BACE1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
451-501/501 |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human BACE1 |
| Gene ID number: |
23621 |
| Swiss Prot: |
P56817 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Cleaves at the N-terminus of the A-beta peptide sequence, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, Responsible for the proteolytic processing of the amyloid precursor protein (APP) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Asp 2, Aspartyl protease 2, BACE, BACE1, Beta-secretase 1, Beta-site APP cleaving enzyme 1, Beta-site amyloid precursor protein cleaving enzyme 1, HSPC104, KIAA1149, Memapsin-2, Membrane-associated aspartic protease 2, ASP2 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
BACE1 |
| Short name: |
BACE1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
BACE1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
933 |
| Gene: |
BACE1 |
More about : BACE1 |
| Long gene name: |
beta-secretase 1 |
| Synonyms gene: |
BACE |
| Synonyms gene name: |
beta-site APP-cleaving enzyme beta-site APP-cleaving enzyme 1 |
| Locus: |
11q23, 3 |
| Discovery year: |
1999-10-29 |
| GenBank acession: |
AF190725 |
| Entrez gene record: |
23621 |
| Pubmed identfication: |
10531052 |
| Havana BLAST/BLAT: |
OTTHUMG00000160636 |