| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
BACE1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
Western blot: 1:1000 |
| Notes: |
Titration of the BACE antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This BACE antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P56817 |
| Purity: |
Purified |
| Description: |
Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, This protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi, one of which is BACE, Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease |
| Immunogen: |
A portion of amino acids 476-501 from the human protein was used as the immunogen for this BACE antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the BACE antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
BACE1 |
| Short name: |
BACE1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
BACE1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
933 |
| Gene: |
BACE1 |
More about : BACE1 |
| Long gene name: |
beta-secretase 1 |
| Synonyms gene: |
BACE |
| Synonyms gene name: |
beta-site APP-cleaving enzyme beta-site APP-cleaving enzyme 1 |
| Locus: |
11q23, 3 |
| Discovery year: |
1999-10-29 |
| GenBank acession: |
AF190725 |
| Entrez gene record: |
23621 |
| Pubmed identfication: |
10531052 |
| Havana BLAST/BLAT: |
OTTHUMG00000160636 |