| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
PDGFR beta (CD140b) |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, FACS, IF, WB, IHC |
| Recommended dilutions: |
Flow Cytometry: 1:10-1:50, IHC (Paraffin): 1:10-1:50, Immunofluorescence: 1:10-1:50, Western blot: 1:1000 |
| Notes: |
Titration of the PDGFR beta antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This PDGFR beta antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P09619 |
| Purity: |
Purified |
| Description: |
A translocation between chromosomes 5 and 12, ETS, The gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor, The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, These growth factors are mitogens for cells of mesenchymal origin, all three genes may be implicated in the 5-q syndrome, composed of both platelet-derived growth factor receptor alpha and beta polypeptides, leukemia gene, results in chronic myelomonocytic leukemia, that fuses the gene to that of the translocation, PDGFRB is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family |
| Immunogen: |
A portion of amino acids 40-72 from the human protein was used as the immunogen for this CD140b / PDGFR beta antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot the PDGFR beta antibody and store frozen at -20 deg, Store at 4oC for up to one month |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
PDGFR beta (CD140b) |
| Short name: |
PDGFR beta Antibody (CD140b) |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
PDGFR b (Antibody to) (CD140b) |
| Alternative technique: |
antibodies |
| Identity: |
8804 |
| Gene: |
PDGFRB |
More about : PDGFRB |
| Long gene name: |
platelet derived growth factor receptor beta |
| Synonyms gene: |
PDGFR |
| Synonyms gene name: |
beta polypeptide , platelet-derived growth factor receptor |
| Synonyms: |
JTK12 CD140b PDGFR1 |
| Locus: |
5q32 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
M21616 |
| Entrez gene record: |
5159 |
| RefSeq identity: |
NM_002609 |
| Classification: |
I-set domain containing CD molecules Immunoglobulin like domain containing Receptor Tyrosine Kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000130053 |