| Also known as: |
PDGFRB / PDGFR Beta |
| Other names: |
Beta platelet-derived growth factor receptor, Beta-type platelet-derived growth factor receptor, CD140 antigen-like family member B, CD140 antigen-like family member B, CD_antigen: CD140b, PDGF-R-beta, PDGFR-1, PDGFR-beta, Platelet-derived growth factor receptor 1, Platelet-derived growth factor receptor beta, beta polypeptide, beta-type platelet-derived growth factor receptor, platelet-derived growth factor receptor, platelet-derived growth factor receptor 1, platelet-derived growth factor receptor beta, platelet-derived growth factor receptor beta |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
PDGFRB |
| Other gene names: |
CD140B, IBGC4, IMF1, JTK12, PDGF-R-beta, PDGFR, PDGFR, PDGFR-1, PDGFR-1, PDGFR-beta, PDGFR1, PDGFR1, PDGFRB, PDGFRB |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
42G12 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, Mouse (Mus musculus), Rat (Rattus norvegicus), the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Human PDGFR beta |
| Purification method: |
Protein G Purified |
| Form/Appearance: |
0, 50% glycerol, pH 7, 09% azide, 2, PBS |
| Concentration: |
1 miligram per 1 mililiter |
| Storage and shipping: |
the antibody should be kept at -20 degrees Celsius, For optimal long term storage |
| Tested applications:: |
Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ 42G12] (IgG1) PDGFRB / PDGFR Beta |
| Short name: |
Mouse Monoclonal [clone 42G12] (IgG1) PDGFRB / PDGFR Beta Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG1 |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
b polypeptide / PDGFR b (Antibody to), sapiens platelet-derived growth factor receptor, Mouse monoclonal [clonality 42G12] (IgG1) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, CD140B and IBGC4 and IMF1 and JTK12 and PDGFR and PDGFR-1 and PDGFR1, PDGFRB and IDBG-53326 and ENSG00000113721 and 5159, Pdgfrb and IDBG-150834 and ENSMUSG00000024620 and 18596, beta polypeptide, nuclei, this GO :0001701 and in utero embryonic development and biological process this GO :0001822 and kidney development and biological process this GO :0001894 and tissue homeostasis and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004714 and transmembrane receptor protein tyrosine kinase activity and molecular function this GO :0004871 and signal transducer activity and molecular function this GO :0004992 and platelet activating factor receptor activity and molecular function this GO :0005017 and platelet-derived growth factor-activated receptor activity and molecular function this GO :0005019 and platelet-derived growth factor beta-receptor activity and molecular function this GO :0005102 and receptor binding and molecular function this GO :0005161 and platelet-derived growth factor receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006024 and glycosaminoglycan biosynthetic process and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0006807 and nitrogen compound metabolic process and biological process this GO :0007165 and signal transduction and biological process this GO :0007169 and transmembrane receptor protein tyrosine kinase signaling pathway and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0009636 and response to toxic substance and biological process this GO :0009986 and cell surface and cellular component this GO :0010863 and positive regulation of phospholipase C activity and biological process this GO :0014068 and positive regulation of phosphatidylinositol 3-kinase signaling and biological process this GO :0014070 and response to organic cyclic compound and biological process this GO :0014911 and positive regulation of smooth muscle cell migration and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016023 and cytoplasmic membrane-bounded vesicle and cellular component this GO :0016301 and kinase activity and molecular function this GO :0016324 and apical plasma membrane and cellular component this GO :0016477 and cell migration and biological process this GO :0016772 and transferase activity, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0004714 : transmembrane receptor protein tyrosine kinase activity and also this GO :0004871 : signal transducer activity and also this GO :0004992 : platelet activating factor receptor activity and also this GO :0005017 : platelet-derived growth factor-activated receptor activity and also this GO :0005019 : platelet-derived growth factor beta-receptor activity and also this GO :0005102 : receptor binding and also this GO :0005161 : platelet-derived growth factor receptor binding and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016301 : kinase activity and also this GO :0016772 : transferase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0004714 : transmembrane receptor protein tyrosine kinase activity, this GO :0004871 : signal transducer activity, this GO :0004992 : platelet activating factor receptor activity, this GO :0005017 : platelet-derived growth factor-activated receptor activity, this GO :0005019 : platelet-derived growth factor beta-receptor activity, this GO :0005102 : receptor binding, this GO :0005161 : platelet-derived growth factor receptor binding, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016301 : kinase activity, this GO :0016772 : transferase activity, this GO :0019901 : protein kinase binding, this GO :0038085 : vascular endothelial growth factor binding, this GO :0043548 : phosphatidylinositol 3-kinase binding, this GO :0048407 : platelet-derived growth factor binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0019901 : protein kinase binding and also this GO :0038085 : vascular endothelial growth factor binding and also this GO :0043548 : phosphatidylinositol 3-kinase binding and also this GO :0048407 : platelet-derived growth factor binding, transferring phosphorus-containing groups and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0019901 and protein kinase binding and molecular function this GO :0030325 and adrenal gland development and biological process this GO :0030335 and positive regulation of cell migration and biological process this GO :0031226 and intrinsic component of plasma membrane and cellular component this GO :0032355 and response to estradiol and biological process this GO :0032516 and positive regulation of phosphoprotein phosphatase activity and biological process this GO :0032526 and response to retinoic acid and biological process this GO :0032956 and regulation of actin cytoskeleton organization and biological process this GO :0032967 and positive regulation of collagen biosynthetic process and biological process this GO :0033993 and response to lipid and biological process this GO :0034405 and response to fluid shear stress and biological process this GO :0035441 and cell migration involved in vasculogenesis and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0035789 and metanephric mesenchymal cell migration and biological process this GO :0035791 and platelet-derived growth factor receptor-beta signaling pathway and biological process this GO :0035793 and positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway and biological process this GO :0035909 and aorta morphogenesis and biological process this GO :0036120 and cellular response to platelet-derived growth factor stimulus and biological process this GO :0038085 and vascular endothelial growth factor binding and molecular function this GO :0038091 and positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0042060 and wound healing and biological process this GO :0042542 and response to hydrogen peroxide and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043202 and lysosomal lumen and cellular component this GO :0043406 and positive regulation of MAP kinase activity and biological process this GO :0043548 and phosphatidylinositol 3-kinase binding and molecular function this GO :0043552 and positive regulation of phosphatidylinositol 3-kinase activity and biological process this GO :0043627 and response to estrogen and biological process this GO :0045087 and innate immune response and biological process this GO :0045840 and positive regulation of mitosis and biological process this GO :0046488 and phosphatidylinositol metabolic process and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0048008 and platelet-derived growth factor receptor signaling pathway and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048015 and phosphatidylinositol-mediated signaling and biological process this GO :0048407 and platelet-derived growth factor binding and molecular function this GO :0048661 and positive regulation of smooth muscle cell proliferation and biological process this GO :0048705 and skeletal system morphogenesis and biological process this GO :0048745 and smooth muscle tissue development and biological process this GO :0048839 and inner ear development and biological process this GO :0050730 and regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0050921 and positive regulation of chemotaxis and biological process this GO :0055003 and cardiac myofibril assembly and biological process this GO :0055093 and response to hyperoxia and biological process this GO :0060326 and cell chemotaxis and biological process this GO :0060981 and cell migration involved in coronary angiogenesis and biological process this GO :0061298 and retina vasculature development in camera-type eye and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process this GO :0071670 and smooth muscle cell chemotaxis and biological process this GO :0072075 and metanephric mesenchyme development and biological process this GO :0072262 and metanephric glomerular mesangial cell proliferation involved in metanephros development and biological process this GO :0072275 and metanephric glomerulus morphogenesis and biological process this GO :0072277 and metanephric glomerular capillary formation and biological process this GO :0072278 and metanephric comma-shaped body morphogenesis and biological process this GO :0072284 and metanephric S-shaped body morphogenesis and biological process this GO :0090280 and positive regulation of calcium ion import and biological process this GO :2000379 and positive regulation of reactive oxygen species metabolic process and biological process this GO :2000573 and positive regulation of DNA biosynthetic process and biological process, 74208 and IDBG-646273 and ENSBTAG00000002804 and 527165, platelet-derived growth factor receptor |
| Identity: |
8804 |
| Gene: |
PDGFRB |
More about : PDGFRB |
| Long gene name: |
platelet derived growth factor receptor beta |
| Synonyms gene: |
PDGFR |
| Synonyms gene name: |
beta polypeptide , platelet-derived growth factor receptor |
| Synonyms: |
JTK12 CD140b PDGFR1 |
| Locus: |
5q32 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
M21616 |
| Entrez gene record: |
5159 |
| RefSeq identity: |
NM_002609 |
| Classification: |
I-set domain containing CD molecules Immunoglobulin like domain containing Receptor Tyrosine Kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000130053 |