| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
FGFR2 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, FACS, IF, IHC, WB |
| Recommended dilutions: |
Flow Cytometry: 1:10-1:50, IHC (Paraffin): 1:50-1:100, Immunofluorescence: 1:10-1:50, Western blot: 1:1000 |
| Notes: |
Titration of the FGFR2 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This FGFR2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P21802 |
| Purity: |
Purified |
| Description: |
Alternative splicing in multiple exons, Isoform 1 has equal affinity for aFGF and bFGF but does not bind KGF, This particular family member is a high-affinity receptor for acidic, and in the regulation of embryonic development, basic and/or keratinocyte growth factor, depending on the isoform, differentiation, including those encoding the Ig-like domains, migration and apoptosis, results in varied isoforms which differ in structure and specificity, the transmembrane region and the carboxyl terminus, Fibroblast growth factor receptor 2 is a tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation |
| Immunogen: |
A portion of amino acids 794-821 from the human protein was used as the immunogen for this FGFR2 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the FGFR2 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
FGFR2 |
| Short name: |
FGFR2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
FGFR2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3689 |
| Gene: |
FGFR2 |
More about : FGFR2 |
| Long gene name: |
fibroblast growth factor receptor 2 |
| Synonyms gene: |
KGFR BEK CFD1 JWS |
| Synonyms gene name: |
bacteria-expressed kinase keratinocyte growth factor receptor craniofacial dysostosis 1 Jackson-Weiss syndrome |
| Synonyms: |
CEK3 TK14 TK25 ECT1 K-SAM CD332 |
| Synonyms name: |
Crouzon syndrome Pfeiffer syndrome |
| Locus: |
10q26, 13 |
| Discovery year: |
1991-05-09 |
| GenBank acession: |
AK026508 |
| Entrez gene record: |
2263 |
| RefSeq identity: |
NM_022976 NM_000141 |
| Classification: |
I-set domain containing CD molecules Receptor Tyrosine Kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000019175 |
| Locus Specific Databases: |
LRG_994 |