| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
JNK |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, IHC, WB, IF |
| Recommended dilutions: |
IHC (Paraffin): 1:10-1:50, Immunofluorescence: 1:10-1:50, Western blot: 1:1000 |
| Notes: |
Titration of the JNK antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This JNK antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P45983 |
| Purity: |
Purified |
| Description: |
MAP kinases act as an integration point for multiple biochemical signals, Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis, This kinase is activated by various cell stimuli, This kinase is also involved in UV radiation induced apoptosis, and are involved in a wide variety of cellular processes such as proliferation, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli, apoptosis and differentiation, differentiation, transcription regulation and development, which is thought to be related to cytochrom c-mediated cell death pathway, JNK1 is a member of the MAP kinase family |
| Immunogen: |
A portion of amino acids 358-389 from the human protein was used as the immunogen for this JNK antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the JNK antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
JNK |
| Short name: |
JNK Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
JNK (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6881 |
| Gene: |
MAPK8 |
More about : MAPK8 |
| Long gene name: |
mitogen-activated protein kinase 8 |
| Synonyms gene: |
PRKM8 |
| Synonyms: |
JNK JNK1 SAPK1 |
| Synonyms name: |
JUN N-terminal kinase |
| Locus: |
10q11, 22 |
| Discovery year: |
1998-04-28 |
| GenBank acession: |
L26318 |
| Entrez gene record: |
5599 |
| Pubmed identfication: |
8137421 8654373 |
| Classification: |
Mitogen-activated protein kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000018172 |