| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
AKT3 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Primate, Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB, IHC |
| Recommended dilutions: |
IHC (Paraffin): 1:50-1:100, Western blot: 1:1000 |
| Notes: |
Titration of the AKT3 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This AKT3 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q9Y243 |
| Purity: |
Purified |
| Description: |
AKT2 and AKT3) called the AKT kinase, AKT3 is the least studied AKT isoform, AKT3 isoform may also be the key molecule in up-regulation and down-regulation of MMP13 via IL13, Down-regulation by RNA interference reduces the expression of the phosphorylated form of BAD, It plays an important role in brain development and is crucial for the viability of malignant glioma cells, Required for the coordination of mitochondrial biogenesis with growth factor-induced increases in cellular energy demands, [UniProt], and which regulate many processes including metabolism, cell survival, growth and angiogenesis, proliferation, resulting in the induction of caspase-dependent apoptosis, AKT3 is one of 3 closely related serine/threonine-protein kinases (AKT1 |
| Immunogen: |
A portion of amino acids 88-118 from the human protein was used as the immunogen for this AKT3 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the AKT3 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
AKT3 |
| Short name: |
AKT3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
AKT3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
393 |
| Gene: |
AKT3 |
More about : AKT3 |
| Long gene name: |
AKT serine/threonine kinase 3 |
| Synonyms gene name: |
v-akt murine thymoma viral oncogene homolog 3 |
| Synonyms: |
PKBG RAC-gamma PRKBG |
| Synonyms name: |
gamma , protein kinase B |
| Locus: |
1q43-q44 |
| Discovery year: |
1999-11-16 |
| GenBank acession: |
AF124141 |
| Entrez gene record: |
10000 |
| Pubmed identfication: |
10092583 10208883 |
| RefSeq identity: |
NM_181690 |
| Classification: |
Pleckstrin homology domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000039994 |