| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
AKT3 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ICC, IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Immunocytochemistry: 0, Western blot: 0 |
| Notes: |
Titration of the AKT3 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This AKT3 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q9Y243 |
| Purity: |
Antigen affinity |
| Description: |
AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors, AKT3 isoform may also be the key molecule in up-regulation and down-regulation of MMP13 via IL13, AKT3 plays an important role in brain development and is crucial for the viability of malignant glioma cells, The protein encoded by this gene is a member of the AKT, They are involved in a wide variety of biological processes including cell proliferation, This gene is mapped to 1q43-q44, This gene is required for the coordination of mitochondrial biogenesis with growth factor-induced increases in cellular energy demands, This kinase has been shown to be stimulated by platelet-derived growth factor(PDGF), also called PKB, and insulin-like growth factor 1(IGF1), apoptosis, as well as glycogen synthesis and glucose uptake, differentiation, insulin, serine/threonine protein kinase family, tumorigenesis, RAC-gamma serine/threonine-protein kinase is an enzyme that in humans is encoded by the AKT3 gene |
| Immunogen: |
mouse and rat), Amino acids 122-136 (TSQIDNIGEEEMDAS) were used as the immunogen for this AKT3 antibody (100% homologous in human |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the AKT3 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
AKT3 |
| Short name: |
AKT3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
AKT3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
393 |
| Gene: |
AKT3 |
More about : AKT3 |
| Long gene name: |
AKT serine/threonine kinase 3 |
| Synonyms gene name: |
v-akt murine thymoma viral oncogene homolog 3 |
| Synonyms: |
PKBG RAC-gamma PRKBG |
| Synonyms name: |
gamma , protein kinase B |
| Locus: |
1q43-q44 |
| Discovery year: |
1999-11-16 |
| GenBank acession: |
AF124141 |
| Entrez gene record: |
10000 |
| Pubmed identfication: |
10092583 10208883 |
| RefSeq identity: |
NM_181690 |
| Classification: |
Pleckstrin homology domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000039994 |