| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
cIAP2 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, IHC, WB |
| Recommended dilutions: |
IHC (Paraffin): 1:10-1:50, Western blot: 1:1000 |
| Notes: |
Titration of the cIAP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This cIAP2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q13489 |
| Purity: |
Antigen affinity |
| Description: |
The amino acid sequence predicts three baculovirus IAP repeat domains and a ring finger domain, The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals, probably by interfering with activation of ICE-like proteases, BIRC3 is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 |
| Immunogen: |
A portion of amino acids 101-131 from the human protein was used as the immunogen for this cIAP2 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the cIAP2 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
cIAP2 |
| Short name: |
cIAP2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
cIAP2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
591 |
| Gene: |
BIRC3 |
More about : BIRC3 |
| Long gene name: |
baculoviral IAP repeat containing 3 |
| Synonyms gene: |
API2 |
| Synonyms gene name: |
baculoviral IAP repeat-containing 3 |
| Synonyms: |
cIAP2 hiap-1 MIHC RNF49 MALT2 c-IAP2 |
| Synonyms name: |
apoptosis inhibitor 2 TNFR2-TRAF signaling complex protein mammalian IAP homolog C inhibitor of apoptosis protein 1 |
| Locus: |
11q22, 2 |
| Discovery year: |
1998-06-10 |
| GenBank acession: |
L49432 |
| Entrez gene record: |
330 |
| Pubmed identfication: |
8552191 8548810 |
| RefSeq identity: |
NM_001165 |
| Classification: |
Baculoviral IAP repeat containing Ring finger proteins Caspase recruitment domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000167324 |