JNK Antibody (phospho-T183/Y185)

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Catalog number: F48652-0.08ML
Price: 350 €
Supplier: Bioss Primary Conjugated Antibodies
Product name: JNK Antibody (phospho-T183/Y185)
Quantity: 0.1ml
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Category: Antibody
Concentration: 09% sodium azide, 4 with 0, In 1X PBS pH 7
Form: Antigen affinity purified
Conjugation: Unconjugated
Clone: Polyclonal antibody
Recognised antigen: JNK (phospho-T183/Y185)
Host animal: Rabbit (Oryctolagus cuniculus)
Clonality: Polyclonal (rabbit origin)
Species reactivity: Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications: ELISA, DB
Recommended dilutions: Dot blot: 1:500
Notes: Titration of the p-JNK antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented use: This p-JNK antibodyis to be used only for research purposes and not for diagnostics
Uniprot #: P45983
Purity: Antigen affinity
Description: Four alternatively spliced transcript variants encoding distinct isoforms have been reported, MAP kinases act as an integration point for multiple biochemical signals, Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis, This kinase is activated by various cell stimuli, This kinase is also involved in UV radiation induced apoptosis, and are involved in a wide variety of cellular processes such as proliferation, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli, apoptosis and differentiation, differentiation, transcription regulation and development, which is thought to be related to cytochrom c-mediated cell death pathway, The protein encoded by this gene is a member of the MAP kinase family
Immunogen: This p-JNK antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pT183/Y185 of human JNK1
Storage: Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the p-JNK antibody and store frozen at -20 deg
Properties: C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene target: JNK (phospho-T183/Y185)
Short name: JNK Antibody (phospho-T183/Y185)
Technique: antibodies against human proteins, antibodies for, Antibody
Alternative name: JNK (Antibody to) (phosphorilated-T183/Y185)
Alternative technique: antibodies
Identity: 6881
Gene: MAPK8 | More about : MAPK8
Long gene name: mitogen-activated protein kinase 8
Synonyms gene: PRKM8
Synonyms: JNK JNK1 SAPK1
Synonyms name: JUN N-terminal kinase
Locus: 10q11, 22
Discovery year: 1998-04-28
GenBank acession: L26318
Entrez gene record: 5599
Pubmed identfication: 8137421 8654373
Classification: Mitogen-activated protein kinases
Havana BLAST/BLAT: OTTHUMG00000018172

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