| Long name: |
Biotin Conjugated, ERK1 (T203/Y205) + ERK2 (T183/Y185) Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
ERK1 (Thr203/Tyr205) + ERK2 (Thr183/Tyr185) |
| Specificity: |
This is a highly specific antibody against ERK1 (Thr203/Tyr205) + ERK2 (Thr183/Tyr185) |
| Modification: |
Phosphorylation |
| Modification site: |
Thr183/Tyr 185 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
160-200/358 |
| Subcellular location: |
Cytoplasm |
| Source: |
KLH conjugated synthetic phosphopeptide derived from mouse ERK2 around the phosphorylation site of Thr183 and Tyr 185 |
| Gene ID number: |
26413 |
| Swiss Prot: |
P63085 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Bovine, Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Binds to a [GC]AAA[GC] consensus sequence, DMP1, IFIH1, IFITM1, IRF7, IRF9, LAMP3, OAS1, OAS2, OAS3 and STAT1, Repress the expression of interferon gamma-induced genes, Seems to bind to the promoter of CCL5, Transcriptional activity is independent of kinase activity (By similarity), Acts as a transcriptional repressor |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
ERK ERK2 p41mapk MAPK2 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
ERK1 (T203/Y205) + ERK2 (T183/Y185) Conjugated |
| Short name: |
Conjugated, ERK1 (T203/Y205) + ERK2 (T183/Y185) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, ERK1 (T203/Y205) and ERK2 (T183/Y185) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6871 |
| Gene: |
MAPK1 |
More about : MAPK1 |
| Long gene name: |
mitogen-activated protein kinase 1 |
| Synonyms gene: |
PRKM2 PRKM1 |
| Locus: |
22q11, 22 |
| Discovery year: |
1993-11-05 |
| GenBank acession: |
M84489 |
| Entrez gene record: |
5594 |
| Classification: |
Mitogen-activated protein kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000030508 |
| Locus Specific Databases: |
LRG_786 |