| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Phospho-CHK1 (pS317) |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, IHC, WB, DB |
| Recommended dilutions: |
Dot blot: 1:500, IHC (Paraffin): 1:50-1:100, Western blot: 1:1000 |
| Notes: |
Titration of the phospho-CHK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This phospho-CHK1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
O14757 |
| Purity: |
Antigen affinity |
| Description: |
and that phosphorylation of CDC25A by CHK1 is required for cells to delay cell cycle progression in response to double-strand DNA breaks, CHK1 directly phosphorylates CDC25A during an unperturbed cell cycle |
| Immunogen: |
This phospho-CHK1 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS317 of human CHK1 |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the phospho-CHK1 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Phospho-CHK1 (pS317) |
| Short name: |
Phospho-CHK1 Antibody (pS317) |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
phosphorilated-CHK1 (Antibody to) (pS317) |
| Alternative technique: |
antibodies |
| Identity: |
1925 |
| Gene: |
CHEK1 |
More about : CHEK1 |
| Long gene name: |
checkpoint kinase 1 |
| Synonyms gene name: |
CHK1 (checkpoint, S, pombe) , pombe) homolog CHK1 checkpoint homolog (S |
| Synonyms: |
CHK1 |
| Locus: |
11q24, 2 |
| Discovery year: |
1998-04-21 |
| GenBank acession: |
AF016582 BC017575 |
| Entrez gene record: |
1111 |
| Pubmed identfication: |
9278511 9382850 |
| RefSeq identity: |
NM_001274 |
| Havana BLAST/BLAT: |
OTTHUMG00000165853 |