| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
DCX |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB, IHC |
| Recommended dilutions: |
IHC (Paraffin): 1:10-1:50, Western blot: 1:1000 |
| Notes: |
Titration of the DCX antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This DCX antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
O43602 |
| Purity: |
Antigen affinity |
| Description: |
DCX is a cytoplasmic protein which appears to direct neuronal migration by regulating the organization and stability of microtubules, In addition, It contains two doublecortin domains, Mutations in the gene encoding DCX are a cause of X-linked lissencephaly, and this interaction is important to proper microtubule function in the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation, the regulatory gamma subunit of platelet activating factor acetylhydrolase, this protein interacts with LIS1, which bind microtubules, In the developing cortex |
| Immunogen: |
A portion of amino acids 107-137 from the human protein was used as the immunogen for this DCX antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the DCX antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
DCX |
| Short name: |
DCX Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
DCX (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2714 |
| Gene: |
DCX |
More about : DCX |
| Long gene name: |
doublecortin |
| Synonyms gene name: |
X-linked (doublecortin) , doublecortex, lissencephaly |
| Synonyms: |
SCLH DC LISX DBCN XLIS |
| Synonyms name: |
doublecortex |
| Locus: |
Xq23 |
| Discovery year: |
1998-03-24 |
| GenBank acession: |
AF040254 |
| Entrez gene record: |
1641 |
| Pubmed identfication: |
9489699 9489700 |
| RefSeq identity: |
NM_178153 |
| Classification: |
Doublecortin superfamily |
| Havana BLAST/BLAT: |
OTTHUMG00000022204 |