| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
TSG101 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, IHC, WB |
| Recommended dilutions: |
IHC (Paraffin): 1:50-1:100, Western blot: 1:1000 |
| Notes: |
Titration of the TSG101 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This TSG101 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q99816 |
| Purity: |
Purified |
| Description: |
Acts as a negative growth regulator, Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs), Involved in the budding of many viruses through an interaction with viral proteins that contain a late-budding motif P-[ST]-A-P, May be involved in cell growth and differentiation, Mediates the association between the ESCRT-0 and ESCRT-I complex, Required for completion of cytokinesis, This interaction is essential for viral particle budding of numerous retroviruses, [UniProt], a regulator of vesicular trafficking process, the function requires CEP55, TSG101 is a component of the ESCRT-I complex |
| Immunogen: |
A portion of amino acids 1-30 from the human protein was used as the immunogen for this TSG101 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the TSG101 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
TSG101 |
| Short name: |
TSG101 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
TSG101 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
15971 |
| Gene: |
TSG101 |
More about : TSG101 |
| Long gene name: |
tumor susceptibility 101 |
| Synonyms gene: |
TSG10 |
| Synonyms gene name: |
tumor susceptibility gene 10 tumor susceptibility gene 101 |
| Synonyms: |
VPS23 |
| Locus: |
11p15, 1 |
| Discovery year: |
2001-07-20 |
| GenBank acession: |
U82130 |
| Entrez gene record: |
7251 |
| Pubmed identfication: |
9019400 9241264 |
| RefSeq identity: |
NM_006292 |
| Classification: |
ESCRT-I |
| Havana BLAST/BLAT: |
OTTHUMG00000167725 |