SLUG Antibody (SNAI2)

Catalog number:	F47912-0.08ML Buy Now
Price:	1790 €
Supplier:	MBS Recombinant Proteins
Product name:	SLUG Antibody (SNAI2)
Quantity:	1000ug
Other quantities:	0.08 ml 199€ 0.4 ml 406€
Related search:	nbsp slug amp gene antibodies snail zinc keratinocytes

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Category:	Antibody
Concentration:	pH 7, with 0, 09% sodium azide, 4, In 1X PBS
Form:	Purified
Conjugation:	Unconjugated
Clone:	Polyclonal antibody
Recognised antigen:	SLUG (SNAI2)
Host animal:	Rabbit (Oryctolagus cuniculus)
Clonality:	Polyclonal (rabbit origin)
Species reactivity:	Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications:	ELISA, WB
Recommended dilutions:	Western blot: 1:1000
Notes:	Titration of the SLUG antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented use:	This SLUG antibodyis to be used only for research purposes and not for diagnostics
Uniprot #:	O43623
Purity:	Purified
Description:	Binds to CXCL12 promoter via E-box regions in mesenchymal stem cells and osteoblasts, Binds to E-box2 domain of BSG and activates its expression during TGFB1-induced epithelial-mesenchymal transition (EMT) in hepatocytes, Binds to RUNX2 and SOC9 promoters and may act as a positive and negative transcription regulator, In epidermal keratinocytes, Involved in osteoblast maturation, Involved in the generation and migration of neural crest cells, Involved in the regulation of&, Plays a role in mediating RAF1-induced transcriptional repression of the TJ protein, Plays an essential role in TWIST1-induced EMT and its ability to promote invasion and metastasis, Represses BRCA2 expression by binding to its E2-box-containing silencer and recruiting&, Represses&, [UniProt], binds to the E-box in&, in osteoblasts, occludin (OCLN) and subsequent oncogenic transformation of epithelial cells (By similarity), respectively, &, &, &, &, &, <, <, <, <, <, <, /CDH1 transcription via E-box elements, /a>, /a>, /a>, /a>, /a>, /a>, /search_result, /search_result, /search_result, /search_result, /search_result, /search_result, CTBP1<, E-Cadherin<, HDAC1<, ITGA3<, ITGB1<, ITGB4<, SNAI2/SLUG is a transcriptional repressor that modulates both activator-dependent and basal transcription, a href=, a href=, a href=, a href=, a href=, a href=, and&, and&, expression and cell adhesion and proliferation in epidermal keratinocytes, in breast cells, nbsp, nbsp, nbsp, nbsp, nbsp, nbsp, nbsp, nbsp, nbsp, nbsp, nbsp, php?search_txt=ctbp>, php?search_txt=e-cadherin>, php?search_txt=hdac1>, php?search_txt=itga3>, php?search_txt=itgb1>, php?search_txt=itgb4>, promoter and represses its transcription
Immunogen:	A portion of amino acids 1-30 from the human protein was used as the immunogen for this SLUG antibody
Storage:	Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the SLUG antibody and store frozen at -20 deg
Properties:	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene target:	SLUG (SNAI2)
Short name:	SLUG Antibody (SNAI2)
Technique:	antibodies against human proteins, antibodies for, Antibody
Alternative name:	SLUG (Antibody to) (SNAI2)
Alternative technique:	antibodies
Identity:	11094
Gene:	SNAI2 | More about : SNAI2
Long gene name:	snail family transcriptional repressor 2
Synonyms gene:	SLUG
Synonyms gene name:	slug homolog, zinc finger protein (chicken) snail homolog 2 (Drosophila) snail family zinc finger 2
Synonyms:	SLUGH1 SNAIL2 SLUGH
Locus:	8q11, 21
Discovery year:	1998-07-03
GenBank acession:	U97060
Entrez gene record:	6591
Pubmed identfication:	9337409 9721220
RefSeq identity:	NM_003068
Classification:	Zinc fingers C2H2-type SNAG transcriptional repressors
Havana BLAST/BLAT:	OTTHUMG00000149912

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