| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
p27Kip1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
Western blot: 1:1000 |
| Notes: |
Titration of the p27Kip1 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This p27Kip1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P46527 |
| Purity: |
Antigen affinity |
| Description: |
The degradation of this protein, The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, [provided by RefSeq], and thus controls the cell cycle progression at G1, is required for the cellular transition from quiescence to the proliferative state, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, which shares a limited similarity with CDK inhibitor CDKN1A/p21, This gene encodes a cyclin-dependent kinase inhibitor |
| Immunogen: |
A portion of amino acids 1-30 from the human protein was used as the immunogen for this p27Kip1 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the p27Kip1 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
p27Kip1 |
| Short name: |
p27Kip1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
p27Kip1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
1785 |
| Gene: |
CDKN1B |
More about : CDKN1B |
| Long gene name: |
cyclin dependent kinase inhibitor 1B |
| Synonyms gene name: |
Kip1) , cyclin-dependent kinase inhibitor 1B (p27 |
| Synonyms: |
KIP1 P27KIP1 |
| Locus: |
12p13, 1 |
| Discovery year: |
1995-09-14 |
| GenBank acession: |
AF480891 |
| Entrez gene record: |
1027 |
| Pubmed identfication: |
8033212 |
| RefSeq identity: |
NM_004064 |
| Havana BLAST/BLAT: |
OTTHUMG00000149914 |