| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
p27KIP1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the p27KIP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This p27KIP1 antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
1027 |
| Purity: |
Antigen affinity |
| Description: |
Downregulation of p27KIP1 by CK2-alpha-prime is necessary for development of agonist- and stress-induced cardiac hypertrophy, It encodes a protein which belongs to the Cip/Kip family of cyclin dependent kinase (Cdk) inhibitor proteins, The function of the protein is associated with an aggressive phenotype in human breast cancer, also known as KIP1 or P27, is an enzyme inhibitor that in humans is encoded by the CDKN1B gene, p27KIP1 can inhibit both CDK activation and the kinase activity of assembled and activated cyclin-CDK, Cyclin-dependent kinase inhibitor 1B |
| Immunogen: |
Human partial recombinant protein (AA 10-198) was used as the immunogen for this p27KIP1 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the p27KIP1 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
p27KIP1 |
| Short name: |
p27KIP1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
p27KIP1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
1785 |
| Gene: |
CDKN1B |
More about : CDKN1B |
| Long gene name: |
cyclin dependent kinase inhibitor 1B |
| Synonyms gene name: |
Kip1) , cyclin-dependent kinase inhibitor 1B (p27 |
| Synonyms: |
KIP1 P27KIP1 |
| Locus: |
12p13, 1 |
| Discovery year: |
1995-09-14 |
| GenBank acession: |
AF480891 |
| Entrez gene record: |
1027 |
| Pubmed identfication: |
8033212 |
| RefSeq identity: |
NM_004064 |
| Havana BLAST/BLAT: |
OTTHUMG00000149914 |