| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
STAT-3 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB, IF |
| Recommended dilutions: |
Immunofluorescence: 1:200, Western blot: 1:1000 |
| Notes: |
Titration of the STAT-3 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This STAT-3 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P40763 |
| Purity: |
Antigen affinity |
| Description: |
EGF, HGF, IL5, IL6, In response to cytokines and growth factors, LIF and BMP2, PIAS3 protein is a specific inhibitor of this protein, STAT family members are phosphorylated by the receptor associated kinases, The small GTPase Rac1 has been shown to bind and regulate the activity of this protein, This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, This protein mediates the expression of a variety of genes in response to cell stimuli, Three alternatively spliced transcript variants encoding distinct isoforms have been described, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators, and thus plays a key role in many cellular processes such as cell growth and apoptosis, The protein encoded by this gene is a member of the STAT protein family |
| Immunogen: |
A portion of amino acids 711-743 from the human protein was used as the immunogen for this STAT-3 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the STAT-3 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
STAT-3 |
| Short name: |
STAT-3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Signal transducer and activation on transcription-3 (Antibody to) |
| Alternative technique: |
antibodies |