| Also known as: |
STAT5B / STAT |
| Other names: |
N/A, Signal transducer and activator of transcription 5B, signal transducer and activator of transcription 5B, signal transducer and activator of transcription 5B, transcription factor STAT5B, signal transducer and activator of transcription 5B |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
STAT5B |
| Gene name synonims: |
STAT |
| Other gene names: |
N/A, STAT5, STAT5B, STAT5B |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1, k |
| Clone: |
2D1 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Human STAT5b |
| Purification method: |
Protein A Purified |
| Form/Appearance: |
pH 7, 2, PBS |
| Concentration: |
38 mg/ml |
| Storage and shipping: |
For long term storage aliquot and keep the antibody at -20 degrees Celsius, Freeze-thaw cycles should be avoided in order to retain the activity of the antibody, Store at +4 degrees Celsius for short term storage |
| Tested applications:: |
ELISA (EIA), Immunofluorescence (IF), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ 2D1] (IgG1, k) STAT5B / STAT |
| Short name: |
Mouse Monoclonal [clone 2D1] (IgG1, k) STAT5B / STAT Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG1 |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens signal transducer and activator on transcription 5B / Signal transducer and activation on transcription (Antibody to), Mouse monoclonal [clonality 2D1] (IgG1, k) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DNA-templated and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0006549 and isoleucine metabolic process and biological process this GO :0006573 and valine metabolic process and biological process this GO :0006600 and creatine metabolic process and biological process this GO :0006631 and fatty acid metabolic process and biological process this GO :0006953 and acute-phase response and biological process this GO :0007165 and signal transduction and biological process this GO :0007259 and JAK-STAT cascade and biological process this GO :0007548 and sex differentiation and biological process this GO :0007565 and female pregnancy and biological process this GO :0007595 and lactation and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0019218 and regulation of steroid metabolic process and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0019530 and taurine metabolic process and biological process this GO :0019903 and protein phosphatase binding and molecular function this GO :0019915 and lipid storage and biological process this GO :0030155 and regulation of cell adhesion and biological process this GO :0030856 and regulation of epithelial cell differentiation and biological process this GO :0032355 and response to estradiol and biological process this GO :0032496 and response to lipopolysaccharide and biological process this GO :0032819 and positive regulation of natural killer cell proliferation and biological process this GO :0032825 and positive regulation of natural killer cell differentiation and biological process this GO :0032870 and cellular response to hormone stimulus and biological process this GO :0033077 and T cell differentiation in thymus and biological process this GO :0035259 and glucocorticoid receptor binding and molecular function this GO :0038161 and prolactin signaling pathway and biological process this GO :0040014 and regulation of multicellular organism growth and biological process this GO :0040018 and positive regulation of multicellular organism growth and biological process this GO :0042104 and positive regulation of activated T cell proliferation and biological process this GO :0042448 and progesterone metabolic process and biological process this GO :0043029 and T cell homeostasis and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043434 and response to peptide hormone and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0045086 and positive regulation of interleukin-2 biosynthetic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045471 and response to ethanol and biological process this GO :0045579 and positive regulation of B cell differentiation and biological process this GO :0045588 and positive regulation of gamma-delta T cell differentiation and biological process this GO :0045621 and positive regulation of lymphocyte differentiation and biological process this GO :0045647 and negative regulation of erythrocyte differentiation and biological process this GO :0045931 and positive regulation of mitotic cell cycle and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0045954 and positive regulation of natural killer cell mediated cytotoxicity and biological process this GO :0046449 and creatinine metabolic process and biological process this GO :0046543 and development of secondary female sexual characteristics and biological process this GO :0046544 and development of secondary male sexual characteristics and biological process this GO :0046983 and protein dimerization activity and molecular function this GO :0048541 and Peyer's patch development and biological process this GO :0048661 and positive regulation of smooth muscle cell proliferation and biological process this GO :0050729 and positive regulation of inflammatory response and biological process this GO :0051272 and positive regulation of cellular component movement and biological process this GO :0060397 and JAK-STAT cascade involved in growth hormone signaling pathway and biological process this GO :0070669 and response to interleukin-2 and biological process this GO :0070670 and response to interleukin-4 and biological process this GO :0070672 and response to interleukin-15 and biological process this GO :0071363 and cellular response to growth factor stimulus and biological process this GO :0071364 and cellular response to epidermal growth factor stimulus and biological process, STAT5, STAT5B and IDBG-50532 and ENSG00000173757 and 102723386, STAT5B and IDBG-640180 and ENSBTAG00000010125 and 282376, Stat5b and IDBG-211594 and ENSMUSG00000020919 and 20851, nuclei, protein dimerization activity, this GO :0000255 and allantoin metabolic process and biological process this GO :0000979 and RNA polymerase II core promoter sequence-specific DNA binding and molecular function this GO :0001553 and luteinization and biological process this GO :0001666 and response to hypoxia and biological process this GO :0001779 and natural killer cell differentiation and biological process this GO :0001889 and liver development and biological process this GO :0003677 and DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0003690 and double-stranded DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0004871 and signal transducer activity and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006101 and citrate metabolic process and biological process this GO :0006103 and 2-oxoglutarate metabolic process and biological process this GO :0006105 and succinate metabolic process and biological process this GO :0006107 and oxaloacetate metabolic process and biological process this GO :0006355 and regulation of transcription, this GO :0000979 : RNA polymerase II core promoter sequence-specific DNA binding, this GO :0000979 : RNA polymerase II core promoter sequence-specific DNA binding and also this GO :0003677 : DNA binding and also this GO :0003682 : chromatin binding and also this GO :0003690 : double-stranded DNA binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0004871 : signal transducer activity and also this GO :0005509 : calcium ion binding and also this GO :0005515 : protein binding and also this GO :0019903 : protein phosphatase binding and also this GO :0035259 : glucocorticoid receptor binding and also this GO :0043565 : sequence-specific DNA binding and also this GO :0046983 : protein dimerization activity, this GO :0003677 : DNA binding, this GO :0003682 : chromatin binding, this GO :0003690 : double-stranded DNA binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0004871 : signal transducer activity, this GO :0005509 : calcium ion binding, this GO :0005515 : protein binding, this GO :0019903 : protein phosphatase binding, this GO :0035259 : glucocorticoid receptor binding, this GO :0043565 : sequence-specific DNA binding, this GO :0046983 : protein dimerization activity, 6777, 789476, signal transducer and activator of transcription 5B |
| Identity: |
11367 |
| Gene: |
STAT5B |
More about : STAT5B |
| Long gene name: |
signal transducer and activator of transcription 5B |
| Locus: |
17q21, 2 |
| Discovery year: |
1997-01-28 |
| GenBank acession: |
BC065227 |
| Entrez gene record: |
6777 |
| Pubmed identfication: |
8631883 |
| RefSeq identity: |
NM_012448 |
| Classification: |
SH2 domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000150724 |
| Locus Specific Databases: |
STAT5Bbase: Mutation registry for Growth hormone insensitivity with immunodeficiency LOVD - Leiden Open Variation Database LRG_192 |