| Category: |
Antibody |
| Concentration: |
09% sodium azide, 4 with 0, In 1X PBS pH 7 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
LC3B (MAP1LC3B) |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, ICC, IF |
| Recommended dilutions: |
Immunocytochemistry: 1:10-1:50, Immunofluorescence: 1:10-1:100 |
| Notes: |
Titration of the LC3B antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This LC3B antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q9GZQ8 |
| Purity: |
Antigen affinity |
| Description: |
It is a Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes), LC3B plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production, MAP1LC3B is one of the light chain subunits and can associate with either MAP1A or MAP1B, MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits |
| Immunogen: |
A portion of amino acids 89-122 from the human protein was used as the immunogen for this LC3B antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the LC3B antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
LC3B (MAP1LC3B) |
| Short name: |
LC3B Antibody (MAP1LC3B) |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
LC3B (Antibody to) (MAP1LC3B) |
| Alternative technique: |
antibodies |
| Identity: |
13352 |
| Gene: |
MAP1LC3B |
More about : MAP1LC3B |
| Long gene name: |
microtubule associated protein 1 light chain 3 beta |
| Synonyms: |
ATG8F |
| Locus: |
16q24, 2 |
| Discovery year: |
2002-09-16 |
| GenBank acession: |
AF087871 |
| Entrez gene record: |
81631 |
| Classification: |
Autophagy related |
| Havana BLAST/BLAT: |
OTTHUMG00000137654 |