| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
TRPM4 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
Western blot: 1:1000 |
| Notes: |
Titration of the TRPM4 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This TRPM4 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q8TD43 |
| Purity: |
Antigen affinity |
| Description: |
The activity of the encoded protein increases with increasing intracellular calcium concentration, Two transcript variants encoding different isoforms have been found for this gene, but this channel does not transport calcium, thereby depolarizing the membrane, The protein encoded by this gene is a calcium-activated nonselective ion channel that mediates transport of monovalent cations across membranes |
| Immunogen: |
A portion of amino acids 1121-1149 from the human protein was used as the immunogen for this TRPM4 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the TRPM4 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
TRPM4 |
| Short name: |
TRPM4 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
member 4 (Antibody to), subfamily M, transient receptor potential cation channel |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
ATP binding, Plasma membranes, TRPM4 and IDBG-62419 and ENSG00000130529 and 54795, TRPM4 and IDBG-640445 and ENSBTAG00000006139 and 100295930, Trpm4 and IDBG-182463 and ENSMUSG00000038260 and 68667, member 4, subfamily M, this GO :0002407 and dendritic cell chemotaxis and biological process this GO :0002724 and regulation of T cell cytokine production and biological process this GO :0005216 and ion channel activity and molecular function this GO :0005227 and calcium activated cation channel activity and molecular function this GO :0005262 and calcium channel activity and molecular function this GO :0005516 and calmodulin binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006811 and ion transport and biological process this GO :0006816 and calcium ion transport and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016925 and protein sumoylation and biological process this GO :0034220 and ion transmembrane transport and biological process this GO :0055085 and transmembrane transport and biological process this GO :0070588 and calcium ion transmembrane transport and biological process this GO :0090263 and positive regulation of canonical Wnt signaling pathway and biological process, this GO :0005216 : ion channel activity, this GO :0005216 : ion channel activity and also this GO :0005227 : calcium activated cation channel activity and also this GO :0005262 : calcium channel activity and also this GO :0005516 : calmodulin binding and also this GO :0005524 : ATP binding, this GO :0005227 : calcium activated cation channel activity, this GO :0005262 : calcium channel activity, this GO :0005516 : calmodulin binding, this GO :0005524 : ATP binding, transient receptor potential cation channel |
| Identity: |
17993 |
| Gene: |
TRPM4 |
More about : TRPM4 |
| Long gene name: |
transient receptor potential cation channel subfamily M member 4 |
| Synonyms gene name: |
member 4 , subfamily M, transient receptor potential cation channel |
| Synonyms: |
FLJ20041 |
| Locus: |
19q13, 3 |
| Discovery year: |
2002-01-11 |
| GenBank acession: |
AK000048 |
| Entrez gene record: |
54795 |
| Pubmed identfication: |
11535825 16382100 |
| RefSeq identity: |
NM_017636 |
| Classification: |
Transient receptor potential cation channels |
| Havana BLAST/BLAT: |
OTTHUMG00000183184 |