| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
TRPM4 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
1-0, 5-1ug/ml, 5ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Optimal dilution of the TRPM4 antibody should be determined by the researcher |
| Intented use: |
This TRPM4 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q8TD43 |
| Purity: |
Antigen affinity |
| Description: |
It is mapped to 19q13, The activity of the encoded protein increases with increasing intracellular calcium concentration, The protein encoded by this gene is a calcium-activated nonselective ion channel that mediates transport of monovalent cations across membranes, Two transcript variants encoding different isoforms have been found for this gene, also known as melastatin-4, but this channel does not transport calcium, is a protein that in humans is encoded by the TRPM4 gene, thereby depolarizing the membrane, 33, Transient receptor potential cation channel subfamily M member 4 (hTRPM4) |
| Immunogen: |
Amino acids 1079-1214 of human TRPM4 were used as the immunogen for the TRPM4 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the TRPM4 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Localization: |
membranous, Cytoplasmic |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
TRPM4 |
| Short name: |
TRPM4 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
member 4 (Antibody to), subfamily M, transient receptor potential cation channel |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
ATP binding, Plasma membranes, TRPM4 and IDBG-62419 and ENSG00000130529 and 54795, TRPM4 and IDBG-640445 and ENSBTAG00000006139 and 100295930, Trpm4 and IDBG-182463 and ENSMUSG00000038260 and 68667, member 4, subfamily M, this GO :0002407 and dendritic cell chemotaxis and biological process this GO :0002724 and regulation of T cell cytokine production and biological process this GO :0005216 and ion channel activity and molecular function this GO :0005227 and calcium activated cation channel activity and molecular function this GO :0005262 and calcium channel activity and molecular function this GO :0005516 and calmodulin binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006811 and ion transport and biological process this GO :0006816 and calcium ion transport and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016925 and protein sumoylation and biological process this GO :0034220 and ion transmembrane transport and biological process this GO :0055085 and transmembrane transport and biological process this GO :0070588 and calcium ion transmembrane transport and biological process this GO :0090263 and positive regulation of canonical Wnt signaling pathway and biological process, this GO :0005216 : ion channel activity, this GO :0005216 : ion channel activity and also this GO :0005227 : calcium activated cation channel activity and also this GO :0005262 : calcium channel activity and also this GO :0005516 : calmodulin binding and also this GO :0005524 : ATP binding, this GO :0005227 : calcium activated cation channel activity, this GO :0005262 : calcium channel activity, this GO :0005516 : calmodulin binding, this GO :0005524 : ATP binding, transient receptor potential cation channel |
| Identity: |
17993 |
| Gene: |
TRPM4 |
More about : TRPM4 |
| Long gene name: |
transient receptor potential cation channel subfamily M member 4 |
| Synonyms gene name: |
member 4 , subfamily M, transient receptor potential cation channel |
| Synonyms: |
FLJ20041 |
| Locus: |
19q13, 3 |
| Discovery year: |
2002-01-11 |
| GenBank acession: |
AK000048 |
| Entrez gene record: |
54795 |
| Pubmed identfication: |
11535825 16382100 |
| RefSeq identity: |
NM_017636 |
| Classification: |
Transient receptor potential cation channels |
| Havana BLAST/BLAT: |
OTTHUMG00000183184 |